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Database: UniProt
Entry: H1D086_9FIRM
LinkDB: H1D086_9FIRM
Original site: H1D086_9FIRM 
ID   H1D086_9FIRM            Unreviewed;       531 AA.
AC   H1D086;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-SEP-2017, entry version 38.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=HMPREF9453_01024 {ECO:0000313|EMBL:EHO63037.1};
OS   Dialister succinatiphilus YIT 11850.
OC   Bacteria; Firmicutes; Negativicutes; Veillonellales; Veillonellaceae;
OC   Dialister.
OX   NCBI_TaxID=742743 {ECO:0000313|EMBL:EHO63037.1, ECO:0000313|Proteomes:UP000003277};
RN   [1] {ECO:0000313|EMBL:EHO63037.1, ECO:0000313|Proteomes:UP000003277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIT 11850 {ECO:0000313|EMBL:EHO63037.1,
RC   ECO:0000313|Proteomes:UP000003277};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Morotomi M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA   Alvarado L., Arachchi H.M., Berlin A., Brown A., Chapman S.B.,
RA   Dunbar C., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Dialister succinatiphilus YIT 11850.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EHO63037.1}.
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DR   EMBL; ADLT01000029; EHO63037.1; -; Genomic_DNA.
DR   RefSeq; WP_008859519.1; NZ_JH591187.1.
DR   EnsemblBacteria; EHO63037; EHO63037; HMPREF9453_01024.
DR   PATRIC; fig|742743.3.peg.1044; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000003277; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000003277};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003277}.
FT   DOMAIN      226    358       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      438    507       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     234    241       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   531 AA;  60412 MW;  1CC6471B3161FD28 CRC64;
     MDFFLLWEQV LDYINKNDSQ YYQMFSYNVF PTSMTDTTLV ITPNKPYLVR WINGVYREKL
     EQIVSRIAGK PMKVEVAPPP DSTAPSPQMP VPPAQKEAAA PSPAPAVPLP EDEEPLPTPV
     PQPLPETPAT DPFPKEVAPP DFSNLKPKTA DQVTLPDIRN YESLHEPSLF DTLGTTVETK
     KNFQPNPVNE EYTFETFVHG NCNEIAYQAA YAVAQTATNP NQADQKMNPL FIYGPSGLGK
     THLLHAICNY IHTYKPSLSV LFVSSETFTN ELIDAIQNHT MPKFRAKYRN LDFLLIDDVQ
     FFGSKDSTKM EIFNTFNELF DKKKYIIMTS DRTPSDIDKL EDRLQSRFSS GLVAPISPPD
     YEICCIILQK RAEKMGITLP KDVVDYIASH INTNVRELEG AFNKLVTFSH IKKEPITLSF
     AREALKDQIP IESGQELTVD FIIDTVCKYY GVKKEKLLGN GRPKRIVIPR QIAMYLCRNE
     LHESYPTLRD CFKRKDHSTV LYACERVEND MAKDPQTRAA VEAIKKLLRN R
//
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