ID   H1KL19_METEX            Unreviewed;       526 AA.
AC   H1KL19;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN   ORFNames=MetexDRAFT_3331 {ECO:0000313|EMBL:EHP91762.1};
OS   Methylorubrum extorquens DSM 13060.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=882800 {ECO:0000313|EMBL:EHP91762.1, ECO:0000313|Proteomes:UP000004382};
RN   [1] {ECO:0000313|EMBL:EHP91762.1, ECO:0000313|Proteomes:UP000004382}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 13060 {ECO:0000313|EMBL:EHP91762.1,
RC   ECO:0000313|Proteomes:UP000004382};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Land M.L., Hauser L., Koskimaki J., Halonen O., Pirttila A.,
RA   Frank C., Woyke T.J.;
RT   "The draft genome of Methylobacterium extorquens DSM 13060.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHP91762.1}.
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DR   EMBL; AGJK01000093; EHP91762.1; -; Genomic_DNA.
DR   RefSeq; WP_003601412.1; NZ_AGJK01000093.1.
DR   AlphaFoldDB; H1KL19; -.
DR   PATRIC; fig|882800.3.peg.3288; -.
DR   Proteomes; UP000004382; Unassembled WGS sequence.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 2.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 2.
PE   4: Predicted;
FT   DOMAIN          69..207
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   DOMAIN          319..375
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          507..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   526 AA;  57206 MW;  9B9593EA1A6794B3 CRC64;
     MAWKLSNCRA RITRLMQTVP ASAISVRRFD QGYLQRRVNE LNQRGRRLGL DEAPIANIPN
     NRAVLVDGVH VYVQLIDYHA LLLDHGRETE ASHRRLLQAL HLHYAATDRV VEQFEVQRVD
     YHGPRLHAVV VTPAASERDR VLKALAFAAT LKGTIEEAGR TMGGQRLSTR VRIGLDTGMA
     VAVNSGRGAE PEPLFLGSPA NYAAKLAEGN EPGIFMSDRV RAVLDEGAVG MVQERRVALT
     QDSQYRYANM SQGRPSWDTN DGFTRAKVQE ALRSLQNDAA LSAVTASEAV FHFHHHEPPL
     RTIRFEDLMP SRTVRMPAVS VFADISGFTA YVDACIATGR VQEMTANLHV IRGEMAECSR
     DDFGGRKVRF IGDCLHGLIA EGSRVETDLP ASVDSAVRLA GGLRSSFDLC KTMLPGVGAL
     GLAIALELGP TPITRLGIRG ERSVRCASSK AVSTSETLQS GLEGTQTALG PDATAAAPFR
     IRQLFRYGPV ENLDYEAVET FLGGSPKVPA APAATSPRPE FRAHAS
//