ID H1KMS1_METEX Unreviewed; 576 AA.
AC H1KMS1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:EHP91188.1};
DE Flags: Precursor;
GN ORFNames=MetexDRAFT_3934 {ECO:0000313|EMBL:EHP91188.1};
OS Methylorubrum extorquens DSM 13060.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=882800 {ECO:0000313|EMBL:EHP91188.1, ECO:0000313|Proteomes:UP000004382};
RN [1] {ECO:0000313|EMBL:EHP91188.1, ECO:0000313|Proteomes:UP000004382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 13060 {ECO:0000313|EMBL:EHP91188.1,
RC ECO:0000313|Proteomes:UP000004382};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Koskimaki J., Halonen O., Pirttila A.,
RA Frank C., Woyke T.J.;
RT "The draft genome of Methylobacterium extorquens DSM 13060.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHP91188.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGJK01000126; EHP91188.1; -; Genomic_DNA.
DR RefSeq; WP_003602545.1; NZ_AGJK01000126.1.
DR AlphaFoldDB; H1KMS1; -.
DR GeneID; 72988407; -.
DR PATRIC; fig|882800.3.peg.3873; -.
DR Proteomes; UP000004382; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF4; SLR6042 PROTEIN; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..576
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003551533"
FT TRANSMEM 173..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 27..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 576 AA; 60668 MW; A44966557F3474BF CRC64;
MRVFSASILR TALLTIGLWA GAPTMSAAHE GHDHGNEAQA SPTTTAPRGS SRTEALELVA
IARNGRLAVF LDRVGTNEPV LDATIQAETP EGAATGTPMP DGSYGFDAHW SLHPGEHEVL
FTVTASGASD VFPVTLTVPE PPPEPPAAGA SAWAAGLAAA HDFQRHLKDA DPLPLAIGGI
GFLLGSVVTL LMRGRRYLPA TALVVLVVAL AFAPRAFARE GTGHGDGAAG PQVHQMAVTA
PVGQDLARRQ PDGSIFVPKP TQRVLSVRTV VTASDILRRT VELPGRIVPD PSASGVVQSS
VGGRLSPPES GIFPRLGTRV RKGEVIAYVT PPVQAVDASD MRQRQGELDQ QIAITERRAE
RYRKLAPGGS VSQVQLEDAQ AELKGLLDRR AALDNIRQQP EALKAPVDGV IAEASAVAGQ
MASPGVQVFQ IVDPSRLWVE ALSFDAVAGG QDATARMADG RMLRLAYMGA GLADRSQAVP
MHFAVEGAPP ELRTGQFVTV LAETDAQQKG LALPRTSVVR GGNGQSIVYE HTAPERFEPR
EVRVEPLDAS RVLVVSGVAP GKRIVTQGAE LLNQVR
//
