ID H1S4U0_9BURK Unreviewed; 386 AA.
AC H1S4U0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Cobalt-zinc-cadmium resistance membrane-fusion protein {ECO:0000313|EMBL:EHP42424.1};
GN ORFNames=OR16_14139 {ECO:0000313|EMBL:EHP42424.1};
OS Cupriavidus basilensis OR16.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1127483 {ECO:0000313|EMBL:EHP42424.1, ECO:0000313|Proteomes:UP000005808};
RN [1] {ECO:0000313|EMBL:EHP42424.1, ECO:0000313|Proteomes:UP000005808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OR16 {ECO:0000313|EMBL:EHP42424.1,
RC ECO:0000313|Proteomes:UP000005808};
RX PubMed=22461549; DOI=10.1128/JB.06752-11;
RA Cserhati M., Kriszt B., Szoboszlay S., Toth A., Szabo I., Tancsics A.,
RA Nagy I., Horvath B., Nagy I., Kukolya J.;
RT "De Novo Genome Project of Cupriavidus basilensis OR16.";
RL J. Bacteriol. 194:2109-2110(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHP42424.1}.
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DR EMBL; AHJE01000034; EHP42424.1; -; Genomic_DNA.
DR RefSeq; WP_006158426.1; NZ_AHJE01000034.1.
DR AlphaFoldDB; H1S4U0; -.
DR PATRIC; fig|1127483.3.peg.2828; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000005808; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF4; SLR6042 PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..386
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003553197"
FT DOMAIN 60..304
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 386 AA; 41285 MW; 8261DB32B382F96A CRC64;
MRPHFLLSLT ATAVLLFSLA GCSDEPAPAA EPPKQPPGVV KPEETLQKAL KVAPVATSAF
SEVLRVSGRI DFDEQRVARI GASVTGRVTD LYGILGQEVK AGQVLARLHS SELGAAQMAF
LKAEAQTELQ VRNAERARQL FAADVIGRGE LQRRESELAI SSAEMRAYRD QLRVLGMSAA
AVAQLAKSGS IDSYSPVFSS ISGTVVERNV AQGQVVQPAD ALYTVADLSR VWVVAEVPEQ
QAALVAEGQS VDIEVPSLGN GAGQKQITGK LIYVGRTVNP QTRTVLVRTE LENREGRLKP
AMLASMLIAS APSQQLVIPE SAIVRDGNDE LVYVEQAGGL YRQAKVKLGA ESDGMRVVQS
GVKAGDRIVV DGAFHLDNER KRLEQG
//
