ID H1VGK5_COLHI Unreviewed; 1422 AA.
AC H1VGK5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Aureobasidin A1 biosynthesis complex {ECO:0000313|EMBL:CCF39358.1};
DE Flags: Fragment;
GN ORFNames=CH063_10216 {ECO:0000313|EMBL:CCF39358.1};
OS Colletotrichum higginsianum (strain IMI 349063) (Crucifer anthracnose
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum destructivum species complex.
OX NCBI_TaxID=759273 {ECO:0000313|EMBL:CCF39358.1, ECO:0000313|Proteomes:UP000007174};
RN [1] {ECO:0000313|Proteomes:UP000007174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMI 349063 {ECO:0000313|Proteomes:UP000007174};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
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DR EMBL; CACQ02003452; CCF39358.1; -; Genomic_DNA.
DR STRING; 759273.H1VGK5; -.
DR EnsemblFungi; CCF39358; CCF39358; CH063_10216.
DR VEuPathDB; FungiDB:CH63R_01925; -.
DR eggNOG; KOG1178; Eukaryota.
DR HOGENOM; CLU_000022_0_9_1; -.
DR Proteomes; UP000007174; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR022657; De-COase2_CS.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527:SF16; NONRIBOSOMAL PEPTIDE SYNTHETASE ASQK; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF08241; Methyltransf_11; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00879; ODR_DC_2_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 70..144
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 49..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1422
FT /evidence="ECO:0000313|EMBL:CCF39358.1"
SQ SEQUENCE 1422 AA; 156289 MW; 69129A9F67A93706 CRC64;
MEKQIWHRLR AVLPRYMIPS RVLVLEGGMP LNANGKVDRR ELTRRAQNME RSSMALGGGG
GGGARESPVA PRNEVEAALC EEFADVLGLE VGITDNFFDL GGHSLMATRL AARISRRLEV
RVTVKEIFDQ PILLDLAATL RRGSTQHSAI VPRPYEGPVE QSFAQGRLWF LERLYPGLTW
YLSSFASRLV GDLNVAALQT ALLALEERHE GLRTTFQQID GVNVQVIQPF VPRQLRVVDI
PGGSEEQLML ALKKENSTPF NLEDEPGWRP ALFRLGEKSY VLSIVMHHII SDGWSLDILQ
RELATFYAAS LRNKNPLSRV SPLPIQYRDF AIWQKEDAQV AEQERQLAYW KGQLDGSQPA
TLLSDKPRPS VPSGTAVVHE FTVDGDTYRD LQRFCRKQQT TPFSVLFAAF RATHFRLTGV
EDATIGTPIA NRNRQELEDL IGFFVNLQCI RTSLADDETF GTLVRQVVSA TAAASANQDV
PFDRLVAELR PGTRDVSRHP LVQMTLAVHY QQNLGKLQLE GLSSDPLNAA ETSRFDLELH
FFQQRDRLQG VIMFARDLFD PVSIKSMETV FCEVLRRGLE DPSVPIASMP LTDGLSAITD
NKLDLVARTK YPRDASIPAL FREQVALTGD AIAVKDSTSQ LTYSELDRQS DQLASSLVRR
GFAPETMIGV LAPRSCEAIV ALMGILKAGL AYLPLDVNVP LGRLESILSS IEYKKLLLLG
AGVPVPATQL DDVEFLTIAE ARDGDAKTAV KQLPSPTATS LAYVMFTSGS TGRPKGVMVE
HRGIVRLVKN TNIQTQAQSA VPVGHIANLA FDAATWEIYT ALLNGGSLIC IDHTTVLDVA
ALGRVFEQEK VKAVMFTPAL LKQCLAESPS TIKGLELLFA SGDRLDVQDA LTAQALAKGG
IINALGHTEN TVYSTAFHMR PAELCINGVP VGRAISNSGA LVLDPQQRPV PLGVMGELVL
TGDGVARGYT DAALNKGRFF DMTTADGETT RAYRTGDRAR YRPVDAQMEF FGRMDQQLKI
RGFRVEPAEV EQVLLRHPAV RDAAIVIRKQ PEDVHSVEMV AFLAARDDEM AEIPQNEIAS
RVEGWGNHFE TSTYVDMDQA IDASVVGNDF LGWTSMYDGT DIDKGEMQEW LDDTMDTILD
HQPAGRVLEI GTGSGMILFN LGGGLESYVG LDPSSSAISF VQSKIQSVPA VAGKAQVYVG
TATDVPSLDG LRADLVVTNS VAQYFPSIEY LLQVIDGLTR IPGVKRLVFG DMRSWAINRD
FLASRALRAL GPAATRTEIR RKIAELEDRE EEFLVDPAFF AGLTSQFPDR IWHVEVLPKR
MRATNELSAY RYQAVIHVRG GPSGREPQQA VHVVDPDSWL DFKVSQLDRS GLLGLLQGSP
NAQTIAVGNI PYSRTIVERL LVESLDEPDV PGSLDGAAXI SX
//
