ID H1VZD8_COLHI Unreviewed; 516 AA.
AC H1VZD8;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|EMBL:CCF45600.1};
GN ORFNames=CH063_14635 {ECO:0000313|EMBL:CCF45600.1};
OS Colletotrichum higginsianum (strain IMI 349063) (Crucifer anthracnose
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum destructivum species complex.
OX NCBI_TaxID=759273 {ECO:0000313|EMBL:CCF45600.1, ECO:0000313|Proteomes:UP000007174};
RN [1] {ECO:0000313|Proteomes:UP000007174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMI 349063 {ECO:0000313|Proteomes:UP000007174};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
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DR EMBL; CACQ02007896; CCF45600.1; -; Genomic_DNA.
DR AlphaFoldDB; H1VZD8; -.
DR STRING; 759273.H1VZD8; -.
DR EnsemblFungi; CCF45600; CCF45600; CH063_14635.
DR VEuPathDB; FungiDB:CH63R_08128; -.
DR eggNOG; KOG0941; Eukaryota.
DR HOGENOM; CLU_002173_5_4_1; -.
DR Proteomes; UP000007174; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0000209; P:protein polyubiquitination; IEA:InterPro.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR044611; E3A/B/C-like.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR PANTHER; PTHR45700:SF8; HECT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45700; UBIQUITIN-PROTEIN LIGASE E3C; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:CCF45600.1};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 161..516
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT ACT_SITE 484
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00104"
SQ SEQUENCE 516 AA; 58954 MW; 40309D9E5AEB3D01 CRC64;
MLQEWDGQPE ILCDGSFGGA LSLIAAMYEK RQDLLLGDVQ FRVDYFAERL DSINMPVAWL
THISSGQKKH LLDFPFIFDP STLVSYFRSV NFSKMSRSYE ESSSLQTRMK AIVAPGGLIT
NPHHKLVLQD LLKTASSKYL ILEISRKNVI RDAFDQLWQR EDRELHRPLK IHLGEDAGEE
GFDSGGVQQE FFRLAVAECL NPDYGAFTVD DRTRMAWFVP GSVVPAWKFE ILGLLVSLAV
YNGLTLPITF PKALYRKLLG EPVNELHHIA DGWPDLAMGL TTLLEWDERQ GLVEDVFART
YEFSVSMFGQ PISREMNDQA RSWPQFEATR GKSPVDENPE DAPLVTNENR NAYVSDYIKY
LTDISVRPQY EAFERGFRAC LHPKALRLLT PPLLQSLVEG VQEIDISELR RYTRYVGWDA
SHRGVRDFWS IVKRYDEKMK RRLLEFVTAS DRVPVGGMKN LQFVVQRNGE EEGEGGHLPT
AYTCYGTLLL PEYKDKDVLR ERLAMALENA QGFGFA
//
