GenomeNet

Database: UniProt
Entry: H1X9H7_WEICO
LinkDB: H1X9H7_WEICO
Original site: H1X9H7_WEICO 
ID   H1X9H7_WEICO            Unreviewed;       468 AA.
AC   H1X9H7;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   05-JUL-2017, entry version 40.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:CCF31230.1};
GN   ORFNames=WEISSC39_08845 {ECO:0000313|EMBL:CCF31230.1};
OS   Weissella confusa LBAE C39-2.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Leuconostocaceae;
OC   Weissella.
OX   NCBI_TaxID=1127131 {ECO:0000313|EMBL:CCF31230.1, ECO:0000313|Proteomes:UP000004839};
RN   [1] {ECO:0000313|EMBL:CCF31230.1, ECO:0000313|Proteomes:UP000004839}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LBAE C39-2 {ECO:0000313|EMBL:CCF31230.1,
RC   ECO:0000313|Proteomes:UP000004839};
RA   Amari M., Laguerre S., Gabriel V., Moulis C., Loux V., Klopp C.,
RA   Robert H., Gabriel B., Vuillemin M., Morel S., Remaud-Simeon M.,
RA   Fontagne-Faucher C.;
RT   "Genome sequence of Weissella confusa LBAE C39-2 isolated from a wheat
RT   sourdough.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CAGH01000024; CCF31230.1; -; Genomic_DNA.
DR   RefSeq; WP_003609892.1; NZ_CAGH01000024.1.
DR   EnsemblBacteria; CCF31230; CCF31230; WEISSC39_08845.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000004839; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000004839};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897}.
FT   DOMAIN      163    296       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      376    445       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     171    178       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   468 AA;  52189 MW;  B492D536A6E37C39 CRC64;
     MDPVQLWNAI KEELRATIAQ TFSYANYVET LTPVAVMENE NNTLTLQLAT NHEQVAEEWQ
     DTNSSYNQAF IQAAMIATNK LNGTPTFVIP SVTFLKPQPT SLFEETPTAP AAAPQSNVEI
     SASDFVTQSI LNPEFRFETF VSSDENGEAY AVAQAVADNP GTQWNPLLIY GGVGLGKTHL
     MQAIGNKVLE RNPSAKVKFI TTEDFINDFT DALRRGANAT EAFKQEYRSA DLLLVDDIQF
     LADKDKIQEE FFHTFNAITR ENHQIVLTSD KLPKEIPGLE MRLVTRFAQG YSANITKPDL
     PTRVAILRNK AEQENLNIPN DVIDEIAAAV DTNVRDLEGV FNQVAGKLRF ATAPVTVETA
     RDILETMNFK RQRAITIPII QETVAKFFNV TVQDLNGKKR NKEIVVPRQI AMYIARELTQ
     DSLPQIGRAF GGKDHTTVMH STEKIENAIE NDAVLAGQVQ QIREELSN
//
DBGET integrated database retrieval system