ID   H1Y4Q4_9SPHI            Unreviewed;       553 AA.
AC   H1Y4Q4;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Type I phosphodiesterase/nucleotide pyrophosphatase {ECO:0000313|EMBL:EHQ28098.1};
GN   ORFNames=Mucpa_4007 {ECO:0000313|EMBL:EHQ28098.1};
OS   Mucilaginibacter paludis DSM 18603.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Mucilaginibacter.
OX   NCBI_TaxID=714943 {ECO:0000313|EMBL:EHQ28098.1, ECO:0000313|Proteomes:UP000002774};
RN   [1] {ECO:0000313|EMBL:EHQ28098.1, ECO:0000313|Proteomes:UP000002774}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18603 {ECO:0000313|EMBL:EHQ28098.1,
RC   ECO:0000313|Proteomes:UP000002774};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Held B.,
RA   Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Brambilla E.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The permanent draft genome of Mucilaginibacter paludis DSM 18603.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CM001403; EHQ28098.1; -; Genomic_DNA.
DR   AlphaFoldDB; H1Y4Q4; -.
DR   STRING; 714943.Mucpa_4007; -.
DR   eggNOG; COG1524; Bacteria.
DR   HOGENOM; CLU_034095_0_0_10; -.
DR   OrthoDB; 9766127at2; -.
DR   Proteomes; UP000002774; Chromosome.
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:InterPro.
DR   CDD; cd16016; AP-SPAP; 1.
DR   Gene3D; 3.30.1360.150; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR026263; Alkaline_phosphatase_prok.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR   PANTHER; PTHR10151:SF126; PHOSPHODIESTERASE; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   PIRSF; PIRSF031924; Pi-irrepressible_AP; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PIRSR:PIRSR031924-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002774};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..553
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003558763"
FT   ACT_SITE        87
FT                   /note="Phosphothreonine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-50"
FT   BINDING         108
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
FT   BINDING         169..171
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
SQ   SEQUENCE   553 AA;  60911 MW;  2B44CF9EAC495E4A CRC64;
     MKLKYLSAAL ITGLTLAASA QTKKSVTAPA ATSIPRPKLV VGIVVDQMRW DYLYRFYDRY
     QNNGLKRMLN DGFTCDNTNL DYIPTVTAAG HTCIYTGSVP SIHGMAGNDF IIQATGKTMY
     CTEDTTVKTV GSTSRAGEMS PRNLLTSTVT DELRLATNFR SKVIGIALKD RGGILPAGHT
     ANAAYWFDDA TGNWITSTYY MNDLPAWVKK FNDEKLADKY LKQDWNTLYP INTYQQSTED
     NSPKYEGKFP GMDAPTMPVK TSQMMSKGYG LIRSTPYGNS ITLDMAKAAI ENEHLGKNTV
     TDFLAVSLSS TDYVGHQFGV NAVETEDTYL RLDRDLGSFF TYLDNTVGKG NYTVFLTADH
     GAAHNPTFLT DHGVPAGVWP TTAIQKELNS ILAKKYGIDN LVLSLMNYQV NLNNRVIADK
     KISEYAIKQD CIQFLQKQDG VEYVVDNQNA QAANVPEALK LRIINGYNAE HSGAIEIILK
     PGWFDGHGTT GTTHGTWNPY DTHIPLVFMG WGIPHGHTNA SIHMTDIAPT IAALLHIQTP
     NGNIGLPILE IVK
//