ID H1Y6A1_9SPHI Unreviewed; 378 AA.
AC H1Y6A1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Epoxide hydrolase domain protein {ECO:0000313|EMBL:EHQ24849.1};
GN ORFNames=Mucpa_0663 {ECO:0000313|EMBL:EHQ24849.1};
OS Mucilaginibacter paludis DSM 18603.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Mucilaginibacter.
OX NCBI_TaxID=714943 {ECO:0000313|EMBL:EHQ24849.1, ECO:0000313|Proteomes:UP000002774};
RN [1] {ECO:0000313|EMBL:EHQ24849.1, ECO:0000313|Proteomes:UP000002774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18603 {ECO:0000313|EMBL:EHQ24849.1,
RC ECO:0000313|Proteomes:UP000002774};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Held B.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The permanent draft genome of Mucilaginibacter paludis DSM 18603.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S33 family.
CC {ECO:0000256|ARBA:ARBA00010088}.
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DR EMBL; CM001403; EHQ24849.1; -; Genomic_DNA.
DR RefSeq; WP_008504434.1; NZ_CM001403.1.
DR AlphaFoldDB; H1Y6A1; -.
DR STRING; 714943.Mucpa_0663; -.
DR eggNOG; COG0596; Bacteria.
DR HOGENOM; CLU_019414_0_1_10; -.
DR OrthoDB; 9780765at2; -.
DR Proteomes; UP000002774; Chromosome.
DR GO; GO:0016803; F:ether hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000639; Epox_hydrolase-like.
DR InterPro; IPR010497; Epoxide_hydro_N.
DR InterPro; IPR016292; Epoxide_hydrolase.
DR PANTHER; PTHR21661:SF35; EPOXIDE HYDROLASE; 1.
DR PANTHER; PTHR21661; EPOXIDE HYDROLASE 1-RELATED; 1.
DR Pfam; PF06441; EHN; 1.
DR PIRSF; PIRSF001112; Epoxide_hydrolase; 1.
DR PRINTS; PR00412; EPOXHYDRLASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EHQ24849.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002774}.
FT DOMAIN 3..108
FT /note="Epoxide hydrolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06441"
FT ACT_SITE 171
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001112-1"
FT ACT_SITE 300
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001112-1"
FT ACT_SITE 355
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001112-1"
SQ SEQUENCE 378 AA; 42438 MW; 5DACE18C7AEB39B6 CRC64;
MKISPFKVHI SDASLADLKS RIEHTRWPDS SPEDGWSSGT SLVYLQQLAA YWATTFSWRQ
VECHINSYPN FIAEIDGFDI HFIYIKGKSA QSLPMIITHG WPGSFLEMLT IVPYLIDGDG
LTFDLVIPSI PGFGFSGNPG QKGCNSARVA ELWHQLMSGL GYTRYAVQGG DVGAGIGTCL
AMQHPEAVIG LHLNYIPGSY KPHLPKGDCF TSEEIAFSQT LNEWLTNEGA YSHLHGTKPQ
TLAYGLNDSP VGLAAWILEK NYAWSGHDGY IESVLSKDEL LANITLYWFT QTLPSSIRLY
RENRLQPTLI FREGQYVSTP VAFIRFPKEL PTPPRSYVER GYNIRQWTQA PTGGHFAAWE
QPRILSDDIR QFFKIQVV
//
