ID H2AVR8_KAZAF Unreviewed; 554 AA.
AC H2AVR8;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Bud emergence protein 1 {ECO:0008006|Google:ProtNLM};
GN Name=KAFR0E03160 {ECO:0000313|EMBL:CCF58468.1};
GN ORFNames=KAFR_0E03160 {ECO:0000313|EMBL:CCF58468.1};
OS Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT
OS 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071382 {ECO:0000313|EMBL:CCF58468.1, ECO:0000313|Proteomes:UP000005220};
RN [1] {ECO:0000313|EMBL:CCF58468.1, ECO:0000313|Proteomes:UP000005220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 /
RC NRRL Y-8276 {ECO:0000313|Proteomes:UP000005220};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
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DR EMBL; HE650825; CCF58468.1; -; Genomic_DNA.
DR RefSeq; XP_003957603.1; XM_003957554.1.
DR AlphaFoldDB; H2AVR8; -.
DR STRING; 1071382.H2AVR8; -.
DR GeneID; 13883205; -.
DR KEGG; kaf:KAFR_0E03160; -.
DR eggNOG; KOG4773; Eukaryota.
DR HOGENOM; CLU_014957_0_1_1; -.
DR InParanoid; H2AVR8; -.
DR OrthoDB; 1368965at2759; -.
DR Proteomes; UP000005220; Chromosome 5.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd05992; PB1; 1.
DR CDD; cd06890; PX_Bem1p; 1.
DR CDD; cd11879; SH3_Bem1p_2; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR035550; Bem1/Scd2_PX.
DR InterPro; IPR035549; Bem1/Scd2_SH3_2.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15706:SF2; BUD EMERGENCE PROTEIN 1; 1.
DR PANTHER; PTHR15706; SH3 MULTIPLE DOMAIN; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00018; SH3_1; 2.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005220};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 69..129
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 147..209
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 283..409
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 481..554
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 554 AA; 62741 MW; 755163C5F6E9D6BC CRC64;
MLKNFKLNKR DSGSKSRITS ADISSPTQSQ DSPIKHITTV PIRYLSNSTY SSSPRKSFNV
RNSSKDVLSA EKVVKAHHSY KAHRGIELSF SEGDFFFVVN EDKEWYHVTN PSTNQNGIVP
KQYFEAINKT SRIVCNPVSV NSNTGNLGSL YAIVLYDFKA EKSDELSSFV GENLFICAHH
NYEWFIAKPI GRLGGPGLVP VGFVSIIDIS TGYATGNDVM DDIKSVNLPT VQEWKNHVAK
YKASNIALGS VEEQNNRLSF DSNDKLISSR SASRRNSEIP PLSNFEQIID GSIDSFGLEN
DKYYFDVRCI LAKNKLRKLR RYYQDFYDLQ VKLLDTFPSE SGKLRDKNGQ WTKRIIPYIP
GPVPYVTDTI TQKRKEDLNI YIKDLIKLPE YISHSSMVNS LFELRDNGYD NEVFIEKTMD
NAKANILQEG AAKRISSRQH DSTLTGDDLG LYKKMSQLSL SSSRPQSRPP SVLPPQPVVK
TNKIKFYYKD DIFALKLHGN ITLNELRSKI SPRVDTENFM LKVKLSDGDG EEIKSDEQVI
DVIEAKLKIS VYDL
//
