ID H2B2B8_KAZAF Unreviewed; 344 AA.
AC H2B2B8;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 03-MAY-2023, entry version 46.
DE RecName: Full=Peroxisomal membrane protein PEX13 {ECO:0000256|ARBA:ARBA00034535};
DE AltName: Full=Peroxin-13 {ECO:0000256|ARBA:ARBA00029693};
GN Name=KAFR0L01580 {ECO:0000313|EMBL:CCF60768.1};
GN ORFNames=KAFR_0L01580 {ECO:0000313|EMBL:CCF60768.1};
OS Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT
OS 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071382 {ECO:0000313|EMBL:CCF60768.1, ECO:0000313|Proteomes:UP000005220};
RN [1] {ECO:0000313|EMBL:CCF60768.1, ECO:0000313|Proteomes:UP000005220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 /
RC NRRL Y-8276 {ECO:0000313|Proteomes:UP000005220};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SIMILARITY: Belongs to the peroxin-13 family.
CC {ECO:0000256|ARBA:ARBA00006033}.
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DR EMBL; HE650832; CCF60768.1; -; Genomic_DNA.
DR RefSeq; XP_003959903.1; XM_003959854.1.
DR AlphaFoldDB; H2B2B8; -.
DR STRING; 1071382.H2B2B8; -.
DR GeneID; 13886976; -.
DR KEGG; kaf:KAFR_0L01580; -.
DR eggNOG; KOG3875; Eukaryota.
DR HOGENOM; CLU_034386_2_0_1; -.
DR InParanoid; H2B2B8; -.
DR OrthoDB; 8987at2759; -.
DR Proteomes; UP000005220; Chromosome 12.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-KW.
DR GO; GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro.
DR CDD; cd11771; SH3_Pex13p_fungal; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR007223; Peroxin-13_N.
DR InterPro; IPR035463; Pex13.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR19332; PEROXISOMAL MEMBRANE PROTEIN PEX13; 1.
DR PANTHER; PTHR19332:SF1; PEROXISOMAL MEMBRANE PROTEIN PEX13; 1.
DR Pfam; PF04088; Peroxin-13_N; 1.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000005220};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 212..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 257..323
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 344 AA; 39281 MW; 9CEB2F8A0A6B8692 CRC64;
MSSSSLNPRP KPWESRSSTP RVQHLTTDNH NPGDETPPPL PTTTPPQMIQ NQQPTFYNPD
PYAQGFPTNS YMQPNPYMGS SYGMNSAYGL GVHSGYNMGF TNNSGMNGVN QLTESTRATF
QLLENLIGTI NGFANMLESS YFATYNSFFT LVSFAEEIGR LKEVIGGMFG IFNIFKFIKR
LQRTKESSFV KDFKESYNNK DNDPVKKKRR RLAWKPLIFF FMAVFGFPYL LNKFVNHVNE
RNKRLASNNN NIQLDPTKLE FARAIYNFVP ENPNIEVNLQ KGDLMAILSK KDSFGNDSQW
WKVRTKNGSV GFVPFNYIEV IIRKPNSNSD TNNDSKIERV EQSN
//
