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Database: UniProt
Entry: H2BWZ3_9FLAO
LinkDB: H2BWZ3_9FLAO
Original site: H2BWZ3_9FLAO 
ID   H2BWZ3_9FLAO            Unreviewed;       475 AA.
AC   H2BWZ3;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   05-JUL-2017, entry version 37.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=Gilli_1278 {ECO:0000313|EMBL:EHQ01945.1};
OS   Gillisia limnaea DSM 15749.
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Gillisia.
OX   NCBI_TaxID=865937 {ECO:0000313|EMBL:EHQ01945.1, ECO:0000313|Proteomes:UP000003844};
RN   [1] {ECO:0000313|Proteomes:UP000003844}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15749 {ECO:0000313|Proteomes:UP000003844};
RX   PubMed=23450183; DOI=10.4056/sigs.3216895;
RA   Riedel T., Held B., Nolan M., Lucas S., Lapidus A., Tice H.,
RA   Del Rio T.G., Cheng J.F., Han C., Tapia R., Goodwin L.A., Pitluck S.,
RA   Liolios K., Mavromatis K., Pagani I., Ivanova N., Mikhailova N.,
RA   Pati A., Chen A., Palaniappan K., Land M., Rohde M., Tindall B.J.,
RA   Detter J.C., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Woyke T.;
RT   "Genome sequence of the Antarctic rhodopsins-containing flavobacterium
RT   Gillisia limnaea type strain (R-8282(T)).";
RL   Stand. Genomic Sci. 7:107-119(2012).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; JH594606; EHQ01945.1; -; Genomic_DNA.
DR   RefSeq; WP_006988262.1; NZ_JH594606.1.
DR   EnsemblBacteria; EHQ01945; EHQ01945; Gilli_1278.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000003844; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000003844};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003844}.
FT   DOMAIN      172    308       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   475 AA;  54187 MW;  9BA9DC2E0CAA2D42 CRC64;
     MSKTAQSVWN SCLAFIKDNI TPQAYKTWFE PIQAVKLTDC ALSIQVPSKF FYEWLEEHYV
     KLLKVSLTKE LGEKAKLVYV IKMENTYGNK LPFTEKIPST QRSHMASQEV DVPIKNKNPE
     LRNPFIIPGI RNVKIESQLN PNYNFENFLE GDSNRLARSA GLAVSNKPGG TSFNPLLIFG
     GVGLGKTHLG HAIGVDIKDK YPEKTVLYIS AEKFTQQYIE SVKKNNRNDF IHFYQIIDVL
     IVDDIQLLSG KAGTQDVFFH IFNHLHQNGK QVILTSDKAP VDMQDIEQRL LSRFKWGLSA
     ELLHPDFETR VSIIQSKLYR DGVEMPIDII EFLANNIKTN IRELEGAIIS LIAHSSFNKK
     DITLELAKKI VDNYVKNTKR EVSIDYIQKI VSDYFQMDVE TLQSKTRKRH IVQARQLAMF
     FAKKFTKASL ASIGSQIGKR DHATVLHACK TVDNLAATDK QFKKFVEDLN KKLTL
//
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