ID H2C0N6_9CREN Unreviewed; 478 AA.
AC H2C0N6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=NAD-dependent aldehyde dehydrogenase {ECO:0000313|EMBL:EHP71298.1};
GN ORFNames=MetMK1DRAFT_00001070 {ECO:0000313|EMBL:EHP71298.1};
OS Metallosphaera yellowstonensis MK1.
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Metallosphaera.
OX NCBI_TaxID=671065 {ECO:0000313|EMBL:EHP71298.1, ECO:0000313|Proteomes:UP000003980};
RN [1] {ECO:0000313|EMBL:EHP71298.1, ECO:0000313|Proteomes:UP000003980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MK1 {ECO:0000313|EMBL:EHP71298.1,
RC ECO:0000313|Proteomes:UP000003980};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Cheng J.-F., Goodwin L., Pitluck S., Peters L.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Kozubal M., Macur R.E., Jay Z., Inskeep W., Woyke T.;
RT "Improved High-Quality Draft sequence of Metallosphaera yellowstonensis
RT MK1.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986}.
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DR EMBL; JH597755; EHP71298.1; -; Genomic_DNA.
DR RefSeq; WP_009069457.1; NZ_JH597755.1.
DR AlphaFoldDB; H2C0N6; -.
DR STRING; 671065.MetMK1DRAFT_00001070; -.
DR eggNOG; arCOG01252; Archaea.
DR HOGENOM; CLU_005391_0_0_2; -.
DR OrthoDB; 6342at2157; -.
DR Proteomes; UP000003980; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR42991; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42991:SF1; ALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000003980}.
FT DOMAIN 12..472
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 478 AA; 52612 MW; C15CA2ED16B203E5 CRC64;
MQAIIGEREV SSQKLIEVRN PASGEVVDTV PSLDRDQVRE AIDVAYNSQE KLLAMAVAKR
SKALLQIASL IRESLNDLAV LMTRETGRPI KSSRGEIERT AQIFELAAAE VRRVMEGKYV
PLDAYEFPPG NERRFALVRR EPLGVVAAIT PFNFPAASFA HKVAPALAVG NTVVFKPSSL
TPLTQMRLAT LVLRVFPRGV LNVITGDSTM IGDEFVNNEK VSLITFTGSA SVGLELASRA
VKQGKRVIME LGGSDAMIVL EDADLKRAVK SAVIGRFDFA GQFCNATKRV IVRREVEDQF
LKMLKEELKK LKAGDPLDES VDVAPLISEQ ARDRMREFLE DAVKGGGEIV FQIDVPKHGN
YFPPTVFKAP PKLKLRALWE ETFGPILPVI PVDSDDEAIK VANSTEYGLD ASVFTSNFSR
AYEIATKLKV GTVVINDTTR LRWDNLPFGG VKKSGIGRES IVDTMTEMTE TKLLVYSI
//
