ID H2C1H4_9CREN Unreviewed; 410 AA.
AC H2C1H4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Transposase, IS605 OrfB family, central region {ECO:0000313|EMBL:EHP70095.1};
GN ORFNames=MetMK1DRAFT_00005970 {ECO:0000313|EMBL:EHP70095.1};
OS Metallosphaera yellowstonensis MK1.
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Metallosphaera.
OX NCBI_TaxID=671065 {ECO:0000313|EMBL:EHP70095.1, ECO:0000313|Proteomes:UP000003980};
RN [1] {ECO:0000313|EMBL:EHP70095.1, ECO:0000313|Proteomes:UP000003980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MK1 {ECO:0000313|EMBL:EHP70095.1,
RC ECO:0000313|Proteomes:UP000003980};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Cheng J.-F., Goodwin L., Pitluck S., Peters L.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Kozubal M., Macur R.E., Jay Z., Inskeep W., Woyke T.;
RT "Improved High-Quality Draft sequence of Metallosphaera yellowstonensis
RT MK1.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the transposase 35
CC family. {ECO:0000256|ARBA:ARBA00008761}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the transposase 2
CC family. {ECO:0000256|ARBA:ARBA00011044}.
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DR EMBL; JH597761; EHP70095.1; -; Genomic_DNA.
DR RefSeq; WP_009070500.1; NZ_JH597761.1.
DR AlphaFoldDB; H2C1H4; -.
DR STRING; 671065.MetMK1DRAFT_00005970; -.
DR eggNOG; arCOG00684; Archaea.
DR HOGENOM; CLU_032903_0_0_2; -.
DR OrthoDB; 33968at2157; -.
DR Proteomes; UP000003980; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR InterPro; IPR010095; Cas12f1-like_TNB.
DR InterPro; IPR001959; Transposase.
DR InterPro; IPR021027; Transposase_put_HTH.
DR NCBIfam; NF040570; guided_TnpB; 1.
DR NCBIfam; TIGR01766; IS200/IS605 family accessory protein TnpB-like domain; 1.
DR PANTHER; PTHR30405:SF20; RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED; 1.
DR PANTHER; PTHR30405; TRANSPOSASE; 1.
DR Pfam; PF12323; HTH_OrfB_IS605; 1.
DR Pfam; PF01385; OrfB_IS605; 1.
DR Pfam; PF07282; OrfB_Zn_ribbon; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000003980};
KW Transposition {ECO:0000256|ARBA:ARBA00022578};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 12..53
FT /note="Transposase putative helix-turn-helix"
FT /evidence="ECO:0000259|Pfam:PF12323"
FT DOMAIN 166..278
FT /note="Probable transposase IS891/IS1136/IS1341"
FT /evidence="ECO:0000259|Pfam:PF01385"
FT DOMAIN 294..362
FT /note="Cas12f1-like TNB"
FT /evidence="ECO:0000259|Pfam:PF07282"
FT REGION 391..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 216..250
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 410 AA; 47120 MW; F493303C16B1EB4B CRC64;
MWRARGKSDK IQLSFKYRIY PTREEKLLRV MQVEAKVYNA LLDAVNNARK EGRRMTPKDT
QDMLKDLKIE GKELVYSKAL QMVNNQLWYN INSLHELKKR GRRVGKLRYK KIMKIINYNQ
SGFKVVGDKL ILSKIGEMKV LFHRPLEGEV KGVIIKKSAT GWYAIFQVEV EKKPLEKTGK
VVGIDLGVEK LVTTTDGAVV ENPRVFDEVE KRIKILQQLL SRKKKGSRNY EKVREKLAKM
HEHVKNLMND HIHKVTSWLV EQYDEICVED LDVKEMVEDS ESKVLRKHIL HSNFSKFVSY
LSYKAERAGR RVVKVDPRGT SKTCARCGHV KKDLTLADRV FVCPKCGWVA DRDYNASLNI
LRAGSGLPLE PVDRKPLLYI PFSEGVYSKF PGRSRKSSSR GGDAPSVRAG
//
