ID   H2CCA9_9LEPT            Unreviewed;       723 AA.
AC   H2CCA9;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=Cyclic nucleotide-binding protein {ECO:0000313|EMBL:EHQ06366.1};
GN   ORFNames=Lepil_1682 {ECO:0000313|EMBL:EHQ06366.1};
OS   Leptonema illini DSM 21528.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptonema.
OX   NCBI_TaxID=929563 {ECO:0000313|EMBL:EHQ06366.1, ECO:0000313|Proteomes:UP000005737};
RN   [1] {ECO:0000313|EMBL:EHQ06366.1, ECO:0000313|Proteomes:UP000005737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21528 {ECO:0000313|EMBL:EHQ06366.1,
RC   ECO:0000313|Proteomes:UP000005737};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.-M.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The Improved High-Quality Draft genome of Leptonema illini DSM 21528.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; JH597773; EHQ06366.1; -; Genomic_DNA.
DR   RefSeq; WP_002771830.1; NZ_JH597773.1.
DR   AlphaFoldDB; H2CCA9; -.
DR   STRING; 183.GCA_002009735_02564; -.
DR   HOGENOM; CLU_010941_0_0_12; -.
DR   Proteomes; UP000005737; Unassembled WGS sequence.
DR   CDD; cd00038; CAP_ED; 2.
DR   CDD; cd07738; DdPDE5-like_MBL-fold; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR11635:SF168; CAMP PROTEIN KINASE REGULATORY CHAIN; 1.
DR   PANTHER; PTHR11635; CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN; 1.
DR   Pfam; PF00027; cNMP_binding; 2.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00100; cNMP; 2.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   PROSITE; PS00889; CNMP_BINDING_2; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005737}.
FT   DOMAIN          474..596
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   DOMAIN          608..723
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
SQ   SEQUENCE   723 AA;  83411 MW;  72DC4EC81EFD9A53 CRC64;
     MSKIILTEPY TTLPRGGYLL ETSVGYIQIG SPPETIKDTM MLPRSTPFIF VLPNQFFHVS
     KGISVAELEF PIYYNHFLRQ KKTYVVCTEE QREQFRIVLN EAIFGPEELD LKSDYANGEQ
     SFGFPNMKAE IDYFRGNREM DDLVRFVIFK DNQVRFNNVT IVKRDDGNFE VHDSDWNKKT
     DLPGEVGYNI IYDTGERMPE PYQPPLLGVT CLGPSHGFDP DDNTSGFIMW INHQGVMVDP
     PVNSTEWLRR SNVNPKLINT VILTHCHADH DAGTFQKILE EGKITIFTTV TVMHSFIRKY
     HALTQIPIKE LYTLFDFVPV VIGKTYIING AAFRFNYALH SIPSLSFEFQ FQDQSFIYSS
     DHLNDPDKFK ELLDNGVLTE SRYRDLLDFP WHYDIIYHEA GIPPLHTRVD YLSTLPEEVQ
     KKITVYHISR KSMPPESHLT LAKFGIENTL YPVVKTPPHE EAYRILDALA NVDIFKNFPI
     AKAKEFLTIA DKELYKRGDV IIRKDTAGDK FFILLSGNVR VEGMEQESFE EENVTKRYGT
     YEYFGEASLI LDTLRSADVV AETDVQALTI EKARFLSFIR GTDLMEKFEK LNQIRRTGTW
     ETLSNSRFFR GMTSAQKTSM EILMEEEEIP GGRDLITEGS NFDDVFIIKR GEVDVLHGGR
     TIETLAWGDF CGEIYNFQKG FTSTLTFRTK TTCQVYRISR NGMLHYIHDN PGVYMRLNYV
     YGK
//