ID H2CQH6_9EURO Unreviewed; 318 AA.
AC H2CQH6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
GN Name=RPB1 {ECO:0000313|EMBL:AEX86829.1};
OS Penicillium caperatum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1132859 {ECO:0000313|EMBL:AEX86829.1};
RN [1] {ECO:0000313|EMBL:AEX86829.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 233.81 {ECO:0000313|EMBL:AEX86829.1};
RX PubMed=22308045;
RA Houbraken J., Samson R.A.;
RT "Phylogeny of Penicillium and the segregation of Trichocomaceae into three
RT families.";
RL Stud. Mycol. 70:1-51(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
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DR EMBL; JN121610; AEX86829.1; -; Genomic_DNA.
DR AlphaFoldDB; H2CQH6; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..165
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04983"
FT DOMAIN 192..296
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF05000"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEX86829.1"
FT NON_TER 318
FT /evidence="ECO:0000313|EMBL:AEX86829.1"
SQ SEQUENCE 318 AA; 35099 MW; 8ADDD2283F4FC8AE CRC64;
NIVSPQRNGP LMGIVQDTLC GIYKICRRDI FLTKDQVMNL MLWVPDWDGV IPPPAIMKPR
PRWTGKQMIS MAFPSGLNLV RVDKDSAPLS EKFSPLNDGG LLIQGGQLMY GMLSKKTVGA
SGGGVIHTIF NEYGCDTAVN FFNGAQTIVN YWLLHHGFSI GIGDTIPDRK TIEKIEEAVR
ERKQEVMEIT ASATDNTLEA LPGMNVRETF ESKVSRALNN ARDEAGAATE KGLKDLNNAI
QMARSGSKGS TINISQMTAV VGQQSVEGKR IPFGFAYRTL PHFTKDDYSP ESRGFVENSY
LRGLTATEFF FHAMAGRR
//
