ID H2CQJ5_9EURO Unreviewed; 318 AA.
AC H2CQJ5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
GN Name=RPB1 {ECO:0000313|EMBL:AEX86848.1};
OS Penicillium griseum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1131486 {ECO:0000313|EMBL:AEX86848.1};
RN [1] {ECO:0000313|EMBL:AEX86848.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 277.58 {ECO:0000313|EMBL:AEX86848.1};
RX PubMed=22308045;
RA Houbraken J., Samson R.A.;
RT "Phylogeny of Penicillium and the segregation of Trichocomaceae into three
RT families.";
RL Stud. Mycol. 70:1-51(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
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DR EMBL; JN121629; AEX86848.1; -; Genomic_DNA.
DR AlphaFoldDB; H2CQJ5; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..165
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04983"
FT DOMAIN 190..296
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF05000"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEX86848.1"
FT NON_TER 318
FT /evidence="ECO:0000313|EMBL:AEX86848.1"
SQ SEQUENCE 318 AA; 35121 MW; 5829C18DD9F01223 CRC64;
NIVSPQRNGP LMGIVQDSLC GIYKICRRDI FLTKDQVMNT MLWVPDWDGV IPPPAILKPR
PRWTGKQIIS MAFPSGLNLL RIDKDSSPLS EKFSPLNDGG LLIHGGQLLY GMLSKKTVGA
SGGGVIHTIF NEYGPDTAVN FFNGAQTIVN YWLLHNGFSI GIGDTIPDRL TIEKIEEAVR
ERKKEVEAIT ASATENTLEP LPGMNVRETF ESKVSRALNN ARDEAGAATE KSLKDLNNAI
QMARSGSKGS TINISQMTAV VGQQSVEGKR IPFGFKYRTL PHFTKDDYSP ESRGFVENSY
LRGLTPTEFF FHAMAGRR
//
