ID   H2EAL2_9VIRU            Unreviewed;       341 AA.
AC   H2EAL2;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Putative zinc protease {ECO:0000313|EMBL:AEX61435.1};
GN   ORFNames=c7_L369 {ECO:0000313|EMBL:AEX61435.1};
OS   Megavirus courdo7.
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Megamimivirinae; Megavirus.
OX   NCBI_TaxID=1128135 {ECO:0000313|EMBL:AEX61435.1};
RN   [1] {ECO:0000313|EMBL:AEX61435.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mv13-c7 {ECO:0000313|EMBL:AEX61435.1};
RA   Desnues C., LaScola B., Yutin N., Fournous G., Koonin E., Raoult D.;
RT   "Provirophages and transpovirons: unique mobilome of giant viruses.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JN885991; AEX61435.1; -; Genomic_DNA.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AEX61435.1};
KW   Protease {ECO:0000313|EMBL:AEX61435.1}.
FT   DOMAIN          24..159
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          166..335
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   341 AA;  39463 MW;  8E263C07503F2CA1 CRC64;
     MKYYQKKLHN GINLIMVPDH RLPIITMGFF IRVGLRNETL QHNGIAHFLE HMLFKSTKNR
     NTDVLFQQLD TIGATYNAAT TAEQTYCYLS GSSDNTNFLL DILLDIYLNP KLSNSDIIME
     KKVIIEEMRM RSDSPLTKLY SQLHQQIYRN TSLERDIIGN INTISKINSK DLREFHQKFY
     QPKNTVFVIV GNFNPILIYQ NIKPVLSSMV NNNINSQYLD NYHDEKKIII SNIKNQLEPK
     IFVKKQSELN QIYLLMAFPI LDINDRSLII IDLITQLLSG GFSSKLSKVL REDNGISYTS
     ISYPVLYQDS GIFIIQLIIN PDQLYNAIDI IGNILFEIKK I
//