ID H2FXW6_OCESG Unreviewed; 549 AA.
AC H2FXW6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Glucose-methanol-choline oxidoreductase {ECO:0000313|EMBL:AEY01120.1};
GN OrderedLocusNames=GU3_06820 {ECO:0000313|EMBL:AEY01120.1};
OS Oceanimonas sp. (strain GK1 / IBRC-M 10197).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Oceanimonas.
OX NCBI_TaxID=511062 {ECO:0000313|EMBL:AEY01120.1, ECO:0000313|Proteomes:UP000007742};
RN [1] {ECO:0000313|EMBL:AEY01120.1, ECO:0000313|Proteomes:UP000007742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GK1 {ECO:0000313|EMBL:AEY01120.1,
RC ECO:0000313|Proteomes:UP000007742};
RX PubMed=22461556; DOI=10.1128/JB.00023-12;
RA Parsa Yeganeh L., Azarbaijani R., Sarikhan S., Mousavi H., Ramezani M.,
RA Amoozegar M.A., Shahzadeh Fazeli A., Salekdeh G.H.;
RT "Complete genome sequence of Oceanimonas sp. GK1, a halotolerant bacterium
RT from Gavkhouni Wetland in Iran.";
RL J. Bacteriol. 194:2123-2124(2012).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; CP003171; AEY01120.1; -; Genomic_DNA.
DR AlphaFoldDB; H2FXW6; -.
DR STRING; 511062.GU3_06820; -.
DR KEGG; oce:GU3_06820; -.
DR eggNOG; COG2303; Bacteria.
DR HOGENOM; CLU_002865_7_1_6; -.
DR Proteomes; UP000007742; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000007742}.
FT DOMAIN 256..270
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 84
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 220
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 549 AA; 60262 MW; CC6974D0B4298A2F CRC64;
MSMEFDFIIV GAGSAGCILA SRLSESGRHS VLLLEAGEKD SSPWFKLPVG FAKTYYNPRY
NYMYYSEEEA GMAGRKVYAP RGKVQGGSGS INAMIYVRGQ ASDFDDWAAA GNEGWSYREV
LPYFKKLEQH PAGDNEFHAS SGPIGITPMK GRAHPICDYY LRAAEQLGWP LNDDFNGAGV
EGAGIYETNI RNGQRDSSNT AYLKPALSRP NLSLQRVSMV QRVLVDEQQQ ATGVEVLYQG
RLQQYRARRE VILSAGAVDS PKLLQLSGIG DRATLTCHGI EVRCHLPAVG ENLQDHLCVS
YYYRANMKTL NDTFRSFWGK AWSGLEYLIN RSGPLSMSVN QAGGFFRGSD TEQAPNIQLY
FNPMSYQIPK DSNARLEPEP YSGFLVAFNA CRPTSKGRIE LASSNPQHAA LIKPNYLSTD
KDINEVIQGS RLIRALMQAP ALREITAEEV LPGKAVESEE EMLTYFRENA GSIYHLCGSC
AMGPDPRTAV VDSRLRVHGL NGLRVIDASI FPSITSGNTN AATMMVAEKG ADMVLADHAD
SAGRGHVDS
//
