GenomeNet

Database: UniProt
Entry: H2IYT5_RAHAC
LinkDB: H2IYT5_RAHAC
Original site: H2IYT5_RAHAC 
ID   H2IYT5_RAHAC            Unreviewed;       235 AA.
AC   H2IYT5;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   07-JUN-2017, entry version 40.
DE   RecName: Full=DnaA regulatory inactivator Hda {ECO:0000256|HAMAP-Rule:MF_01158, ECO:0000256|SAAS:SAAS00634471};
GN   Name=hda {ECO:0000256|HAMAP-Rule:MF_01158};
GN   OrderedLocusNames=Rahaq2_3346 {ECO:0000313|EMBL:AEX53150.1};
OS   Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC
OS   105701 / NCIMB 13365 / CIP 78.65).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Rahnella.
OX   NCBI_TaxID=745277 {ECO:0000313|EMBL:AEX53150.1, ECO:0000313|Proteomes:UP000009010};
RN   [1] {ECO:0000313|Proteomes:UP000009010}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 /
RC   CIP 78.65 {ECO:0000313|Proteomes:UP000009010};
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Held B., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sobecky P.,
RA   Martinez R., Woyke T.;
RT   "Complete sequence of chromosome of Rahnella aquatilis CIP 78.65.";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the interaction of DNA replication inititator
CC       protein DnaA with DNA polymerase subunit beta sliding clamp
CC       (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering
CC       DnaA inactive for reinititation, a process called regulatory
CC       inhibition of DnaA or RIDA. {ECO:0000256|HAMAP-Rule:MF_01158}.
CC   -!- SUBUNIT: The active form seems to be an ADP-bound monomer. Forms
CC       the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA,
CC       ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).
CC       {ECO:0000256|HAMAP-Rule:MF_01158}.
CC   -!- SIMILARITY: Belongs to the DnaA family. HdA subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_01158, ECO:0000256|SAAS:SAAS00548763}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP003244; AEX53150.1; -; Genomic_DNA.
DR   RefSeq; WP_015698253.1; NZ_JMPO01000116.1.
DR   STRING; 745277.Rahaq2_3346; -.
DR   EnsemblBacteria; AEX53150; AEX53150; Rahaq2_3346.
DR   KEGG; raq:Rahaq2_3346; -.
DR   PATRIC; fig|745277.3.peg.3205; -.
DR   eggNOG; ENOG4108KZ1; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K10763; -.
DR   OMA; DWGQIYR; -.
DR   OrthoDB; POG091H0GIW; -.
DR   Proteomes; UP000009010; Chromosome.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-HAMAP.
DR   GO; GO:0032297; P:negative regulation of DNA-dependent DNA replication initiation; IEA:InterPro.
DR   HAMAP; MF_01158; Hda; 1.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR017788; Hda.
DR   InterPro; IPR022864; Hda_Enterobact.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   PRINTS; PR00051; DNAA.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03420; DnaA_homol_Hda; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000009010};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_01158,
KW   ECO:0000256|SAAS:SAAS00634466};
KW   DNA replication inhibitor {ECO:0000256|HAMAP-Rule:MF_01158,
KW   ECO:0000256|SAAS:SAAS00634468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009010}.
FT   DOMAIN       18    214       Bac_DnaA. {ECO:0000259|Pfam:PF00308}.
SQ   SEQUENCE   235 AA;  26708 MW;  D8431B37535700BB CRC64;
     MLLNTPAQLS LPLYLPDDET FASFYPGENP SLLSAIQSAL HQEHGTYIYF WSREGGGRSH
     LLHAACAELS QRGEAVGYVP LDKRAYFVPE VLDGMEHLAL VCIDNIEGIA GDDEWEAAVF
     HLYNRILETG RTRLFITGDR PPRQLNLSLP DLASRLDWGQ IYKLQPLSDE EKLQALQLRA
     KLRGFELPED VGRFLLKRLD REMRTLFMTL DQLDRASITA QRKLTIPFVK DILGL
//
DBGET integrated database retrieval system