ID H2JHU3_9CLOT Unreviewed; 300 AA.
AC H2JHU3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Clo1100_2770 {ECO:0000313|EMBL:AEY66928.1};
OS Clostridium sp. BNL1100.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=755731 {ECO:0000313|EMBL:AEY66928.1, ECO:0000313|Proteomes:UP000007324};
RN [1] {ECO:0000313|EMBL:AEY66928.1, ECO:0000313|Proteomes:UP000007324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BNL1100 {ECO:0000313|EMBL:AEY66928.1,
RC ECO:0000313|Proteomes:UP000007324};
RX PubMed=23209234; DOI=10.1128/JB.01908-12;
RA Li L.L., Taghavi S., Izquierdo J.A., van der Lelie D.;
RT "Complete Genome Sequence of Clostridium sp. Strain BNL1100, a Cellulolytic
RT Mesophile Isolated from Corn Stover.";
RL J. Bacteriol. 194:6982-6983(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP003259; AEY66928.1; -; Genomic_DNA.
DR AlphaFoldDB; H2JHU3; -.
DR STRING; 755731.Clo1100_2770; -.
DR KEGG; clb:Clo1100_2770; -.
DR PATRIC; fig|755731.4.peg.2761; -.
DR eggNOG; COG0642; Bacteria.
DR HOGENOM; CLU_000445_89_3_9; -.
DR OrthoDB; 9792991at2; -.
DR Proteomes; UP000007324; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45528; SENSOR HISTIDINE KINASE CPXA; 1.
DR PANTHER; PTHR45528:SF14; SENSOR HISTIDINE KINASE CSSS; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AEY66928.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:AEY66928.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 91..299
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 300 AA; 34243 MW; 0FDE766367827DA8 CRC64;
MKRLSIGIGI LIIIVLLLIL YIVVVQTQLR RINRQLENRL AGDTRQPVRV ELINHELSQL
ISNINKCLKA EETLRLDCVR EEKQFKELIA NISHDLRTPL TAIRGYQQLI EKGQLTEEQR
KRLGIAQKHA EQLGHLVEHF FEYSYLLNSE LKPQMERINL TNLVTECLAG YVSSFEEHGL
TLSFTETPPI FIMADKEMTF RIIQNLLRNC LTHSAGNVEV KLTANKTAVI SIKNPVENTS
QIDITRLFDR FYTGDKSRSK TTGLGLAIVK ILAEELGGNV SADLYKNQLT IHVEFPLIKK
//
