ID H2KRC3_CLOSI Unreviewed; 1116 AA.
AC H2KRC3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 28-JUN-2023, entry version 33.
DE SubName: Full=Sorting nexin-14 {ECO:0000313|EMBL:GAA30572.2};
GN ORFNames=CLF_105969 {ECO:0000313|EMBL:GAA30572.2};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA30572.2, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA30572.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA30572.2};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF143142; GAA30572.2; -; Genomic_DNA.
DR AlphaFoldDB; H2KRC3; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF44; SORTING NEXIN-14; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT DOMAIN 1..169
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 535..661
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 279..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 379..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..445
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 851..882
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 853..873
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1116 AA; 126543 MW; 20574FAE4FD186E3 CRC64;
MKRKHAFLVI RTDDWIESML EDSVLRAFGS HLHICMASRS SELAYMRALV NRILPLISYP
PGLVTPSSIN VERFLKPDSL KHAFSQLKRP ASQSSARSSS IRLVPVHRSL SNQNLPTRQN
EHVSLGANRA AYSFLVEILS TCVLLPAMDA IANPDLLNKF ILLYSEPTED STDCLIEATH
EVPVLNTYVQ EWEKWISEKP PVTLQLERLL RHQEEFHPFM QYMKSIKSAA PLIAVFLISN
INRRVLRDPL PPDTCREIRS QVVHLLSLVR DSVNLDTDHR RLTRGGEEED TTEPQPDRKT
QNPRLFALSA EFETLLTDFL AEPTDADSLD GLVHSTLWRD AYHTASQQIG LHFLPMYLES
PEYLTHVFGS SWFCPPDRPH TPGASRRASQ AEPNRFENPL KGMFAGHTVE GRVLYSLGSD
SNRPSMRLPN RPTKPSSQGL NHRSETLSVQ PHCISSHGDG HHQLRSHYML QSRQIDLSDW
RVYIPGLSRP EVAPGKRLID QLTQGSNPRS DSPTRRAQYS ARPHDASFRS KITDELQNLH
ASSNANRMPQ LSPQFLFTVR TERVVRGVRQ TIARVDSHVH TMCPLSRKYS EFYVLEQKLI
EFHGNAITQT LPPRKFTPRT FEFLESKREL FEEYLQYLIA QPFLRNSELL HGFLTSKMPF
TSSLLFELNL GRFVKSVPLK LIKERGQYLD QFLISFYVSC SPQPILMEPV EPSIEPVFTV
FPSSGVGTLG GIDALATPDH YSLKPSSSSP SSSEATTVSW TVARNHLSAG IGSHRQNPGV
ASSSVIMPRS YKRTWLDNRI RVKMFWNNAG LPVERRHDLR KKSCEFFGVQ PSGLLELAIY
TFKPFAISES GNPPASVDPS MDDNDSTTCE QRSNTLKKTE EESVIPAEPW DIGSSGWNEA
LLTAPTVAPT TEIVAPHSYT DSSIAVQHSE EQSYPPVLGD NSTVGQDRTV SISWEDMIAA
LTGLWRLCSQ HLFTHLRFLL LWIFYILRGY CKTRIDAWFI GRIKQYMQHT LTDDTIANAL
QILKATLFYP PTSPNTDLER LERKAAAGDA LRQRVKNTGL AFIIDSKQLE ERVDKLFLCL
QHPKWNKQLT YVLLDQLVTV LFPELIDQAG NQQPDY
//
