ID   H2KUB5_CLOSI            Unreviewed;       745 AA.
AC   H2KUB5;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Pre-mRNA-splicing factor SYF1 {ECO:0000313|EMBL:GAA31410.2};
GN   ORFNames=CLF_108448 {ECO:0000313|EMBL:GAA31410.2};
OS   Clonorchis sinensis (Chinese liver fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX   NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA31410.2, ECO:0000313|Proteomes:UP000008909};
RN   [1] {ECO:0000313|EMBL:GAA31410.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Henan {ECO:0000313|EMBL:GAA31410.2};
RX   PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA   Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA   Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA   Yu X.;
RT   "The draft genome of the carcinogenic human liver fluke Clonorchis
RT   sinensis.";
RL   Genome Biol. 12:R107-R107(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the crooked-neck family.
CC       {ECO:0000256|ARBA:ARBA00008644}.
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DR   EMBL; DF144047; GAA31410.2; -; Genomic_DNA.
DR   AlphaFoldDB; H2KUB5; -.
DR   Proteomes; UP000008909; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR045075; Syf1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR11246; PRE-MRNA SPLICING FACTOR; 1.
DR   PANTHER; PTHR11246:SF5; PRE-MRNA-SPLICING FACTOR SYF1; 1.
DR   SMART; SM00386; HAT; 10.
DR   SUPFAM; SSF48452; TPR-like; 4.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022728};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00022728};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008909};
KW   Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
SQ   SEQUENCE   745 AA;  85643 MW;  3A9617D52A9766DF CRC64;
     MEDEYVVIMP RIWTDYLLFL MSQGFITRTR RTFDRALKAL PVTQHDRIWG IYLRFADKHG
     SGIGETCLRI YRRYVKFAPD DMERFVEFLV GIGNANEAAL VLADIINDDN FVSRQGRSKF
     QLWQQLCSLL VKNPSKVGLL WNSLADYHIR CGNLLRARDV YAEALNTVMT VRDFTQVFDA
     YAEFEESVAK AKMEALDKSQ SASEEDELDV ELHLARLEAL MDKRPLLLNS VLLRQNPHNV
     SDWLKRVELM KPQGAREQIN TFMEAITSVD PAKAAAGRPS ALWVGLAQLY EKHKQLDDAR
     VVFQKATGVT FVHVEDLASI WCEWAEMELR NDRPEEALRL LGKATTAPPR KVDYYDRSEP
     VQARLHKSLR VWTLYTDLEE SFGTFETTKA AYDHMIDLRI ATPQIIMNYA LFLEEQNYFE
     EAFKAYEKGV ALFRWPNVYD IWAAYLAKFI ERYGGTKLER ARDLFEQCLE KCPPKFAKAL
     YLLYARLEEQ HGLARRAIRI YERATEAVLP GERFDMFNIY IQRIADLHGV THTRSAYEQA
     IERLPEEHAR QMCLRFADLE RKLGEIDRAR AIYAYCSQMC DPRTEPQFWQ VWKEFEVAHG
     NEDTLREMLR IRRSVQATYN TRVSFMASQL QITGADGTEQ ATPTNEMQKL DKAHSDATKP
     QLAGRPVVIF QSAGVRQLGL DAQDQTRSVT TNKEAINIDD IGADDADDGD GQVAEDDADL
     ELNLEKQPVP LAVFGGLKED DEDTS
//