ID H2L5X5_ORYLA Unreviewed; 815 AA.
AC H2L5X5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Protein phosphatase 1, regulatory subunit 13 like {ECO:0000313|Ensembl:ENSORLP00000001212.2};
GN Name=ppp1r13l {ECO:0000313|Ensembl:ENSORLP00000001212.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000001212.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000001212.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000001212.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000001212.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000001212.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004075524.1; XM_004075476.2.
DR RefSeq; XP_011480506.1; XM_011482204.1.
DR RefSeq; XP_011480507.1; XM_011482205.1.
DR RefSeq; XP_011480508.1; XM_011482206.1.
DR AlphaFoldDB; H2L5X5; -.
DR STRING; 8090.ENSORLP00000001212; -.
DR Ensembl; ENSORLT00000001213.2; ENSORLP00000001212.2; ENSORLG00000000990.2.
DR GeneID; 101159370; -.
DR KEGG; ola:101159370; -.
DR CTD; 10848; -.
DR eggNOG; KOG0515; Eukaryota.
DR GeneTree; ENSGT00940000160551; -.
DR HOGENOM; CLU_019814_0_0_1; -.
DR InParanoid; H2L5X5; -.
DR OrthoDB; 5476196at2759; -.
DR TreeFam; TF105545; -.
DR Proteomes; UP000001038; Chromosome 13.
DR Bgee; ENSORLG00000000990; Expressed in pharyngeal gill and 14 other cell types or tissues.
DR GO; GO:0045597; P:positive regulation of cell differentiation; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR028320; iASPP.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24164; RELA-ASSOCIATED INHIBITOR; 1.
DR PANTHER; PTHR24164:SF4; RELA-ASSOCIATED INHIBITOR; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 649..681
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 682..714
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 748..808
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 33..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..538
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..289
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 815 AA; 88742 MW; 6906530DF247D8CE CRC64;
MSSQGSFSTN FLFQSMNDDL NASLATADEL SKEFSSMMKE ASSSPSSSNN NNIKNTTSGS
QSSSTISKDY LQSSGTSSLS STSRSSGSGT NGSSSSKAMS SSSLPYFYST DSSKSSSRNM
PTSQALSQSP HSSPKTEKRG IAPIPRFSSD SYLYSSQNAN PPTSTQLPSS PSLYDRSPQT
FNAYSDRGPS PNVRAGSMDR IPHNSQNASN LLNPYEGGHI GRRSPRSDNN PSPLAFSPPA
ASTLPRNFNP FRQSDEVVQR KKNPGKWSET DLDTSYDRKP HHTYDKTEFL RPAVPKGNWR
ESNLDGPSPS MIPKQPQQVS YGSLNRPTRR SVPPDVPSSA QPPYMPQPIS SRISIPPNVN
LSRQNKPIPL SVILRLQNPR FGAMRTHHPR AVGGEGDRGT HQAAPPQQRE YVRQPPVPVE
QQVPDLKQTA AYSDVLNSRD VDAELERQEY QPTPGNVENP SIPGDGGEVG LPAPPVPRPL
SPTRLQPVVA PEAQVDEIPD REELLRIRAE IPRALKRRGA VELSEPPTEI SMNQPNQYKN
LINKLFRKRG RRHKGEQGSD GSSSSDDEGG SSVPTPTPAV RTAPVTPTLA PQEAKNYRTI
LRRPGRKSSG KRARLSPLVL LLDGALVGEL ETVQKAVQEM TDPSQPNDEG ITGLHNAICG
GHYNVVDFLV RIGANVSAPD SHGWTPLHCA ASCNDLHLCE FLVRNGAAVM AVTERDNATA
AQKCDPYTVG FEECESFLKG VEEAMGVENS GVLYALWSYP AQAADELSFK EGDMVTILHK
PEGSDWWWAS LCGREGFVPN NYFGLFPKVR PKSLC
//
