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Database: UniProt
Entry: H2LDL9_ORYLA
LinkDB: H2LDL9_ORYLA
Original site: H2LDL9_ORYLA 
ID   H2LDL9_ORYLA            Unreviewed;       462 AA.
AC   H2LDL9;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   25-OCT-2017, entry version 37.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSORLP00000004028};
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae;
OC   Oryziinae; Oryzias.
OX   NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000004028, ECO:0000313|Proteomes:UP000001038};
RN   [1] {ECO:0000313|Proteomes:UP000001038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Proteomes:UP000001038};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B.,
RA   Yamada T., Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D.,
RA   Shimada A., Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A.,
RA   Asakawa S., Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K.,
RA   Sugano S., Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F.,
RA   Nomoto H., Nogata K., Morishita T., Endo T., Shin-I T., Takeda H.,
RA   Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome
RT   evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSORLP00000004028}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000004028};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00933551}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSORLP00000004028}.
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DR   EMBL; BAAF04083181; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BAAF04083182; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BAAF04083183; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BAAF04083184; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BAAF04083185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 8090.ENSORLP00000004028; -.
DR   Ensembl; ENSORLT00000004029; ENSORLP00000004028; ENSORLG00000003233.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   GeneTree; ENSGT00760000119180; -.
DR   InParanoid; H2LDL9; -.
DR   OMA; AHININC; -.
DR   OrthoDB; EOG091G029I; -.
DR   TreeFam; TF313147; -.
DR   Proteomes; UP000001038; Chromosome 18.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR005461; TRPC5_channel.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   PANTHER; PTHR10117:SF24; PTHR10117:SF24; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   SMART; SM00248; ANK; 2.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|SAAS:SAAS00933366};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001038};
KW   Ion channel {ECO:0000256|SAAS:SAAS00931870};
KW   Ion transport {ECO:0000256|SAAS:SAAS00929079};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW   Repeat {ECO:0000256|SAAS:SAAS00931009};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00927442}.
FT   TRANSMEM    328    352       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    364    383       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    403    420       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    441    459       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      176    238       TRP_2. {ECO:0000259|Pfam:PF08344}.
FT   DOMAIN      377    453       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      227    254       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   462 AA;  53433 MW;  9BA0C981DC66778B CRC64;
     MTQLYYKKAT YSPYRDRIPL QIVRAEVELS AEERAYLTAV EKGDYAGVKH ALREAEVYYN
     MDVNCLDPLG RSGLLIAIEN ENLEIMELLL DHGIHTGDAL LYAIRKEVVG AVELLLSHRR
     PSGEKQVPSL MMDSQFSEFT PDITPIMLAA HTNNYEIIKL LVQRKVTIPR PHQIRCDCVE
     CVSSSEVDSL RHSRSRLNIY KALASPSLIA LSSEDPILTA FRLGWELKEL SKVENEFRQE
     YEELSQQCKR FAKDLLDQAR SSRELETILN HRDSDQSEEL DPRQCHDLAK LKLAIKYHQK
     EFVAQPNCQQ LLATLWYDGF PGWRRHHWAV KLVTCFIIGL LFPVFSMIYL LAPKSALGRF
     IKKPFIKFIC HTASYLTFLF LLLLASQHIA RTNLHMQGPP PTVVEWMILP WVLGFIWAEI
     KEMWDGGFTE YIHDWWNLMD FAMNSLYLAT ISLKIVAYVK VR
//
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