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Database: UniProt
Entry: H2LFB8_ORYLA
LinkDB: H2LFB8_ORYLA
Original site: H2LFB8_ORYLA 
ID   H2LFB8_ORYLA            Unreviewed;       490 AA.
AC   H2LFB8;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-SEP-2017, entry version 45.
DE   SubName: Full=Potassium voltage-gated channel, shaker-related subfamily, member 1a {ECO:0000313|Ensembl:ENSORLP00000004652};
GN   Name=LOC101161480 {ECO:0000313|Ensembl:ENSORLP00000004652};
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae;
OC   Oryziinae; Oryzias.
OX   NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000004652, ECO:0000313|Proteomes:UP000001038};
RN   [1] {ECO:0000313|Proteomes:UP000001038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Proteomes:UP000001038};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B.,
RA   Yamada T., Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D.,
RA   Shimada A., Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A.,
RA   Asakawa S., Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K.,
RA   Sugano S., Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F.,
RA   Nomoto H., Nogata K., Morishita T., Endo T., Shin-I T., Takeda H.,
RA   Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome
RT   evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSORLP00000004652}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000004652};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSORLP00000004652}.
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DR   EMBL; BAAF04034753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_011474248.1; XM_011475946.1.
DR   STRING; 8090.ENSORLP00000004652; -.
DR   Ensembl; ENSORLT00000004653; ENSORLP00000004652; ENSORLG00000003735.
DR   GeneID; 101161480; -.
DR   KEGG; ola:101161480; -.
DR   eggNOG; KOG1545; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00760000118846; -.
DR   KO; K04874; -.
DR   OMA; DTYPPDH; -.
DR   OrthoDB; EOG091G10NU; -.
DR   TreeFam; TF313103; -.
DR   Proteomes; UP000001038; Chromosome 6.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR   InterPro; IPR004048; K_chnl_volt-dep_Kv1.1.
DR   InterPro; IPR011333; SKP1/BTB/POZ.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01508; KV11CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01496; SHAKERCHANEL.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001038};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00091688}.
FT   TRANSMEM    166    186       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    216    237       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    322    343       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    382    403       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    134       BTB. {ECO:0000259|SMART:SM00225}.
SQ   SEQUENCE   490 AA;  55538 MW;  702BE5B1DD2592CE CRC64;
     MTVVAGDNMD DTSAVPGHPQ DTYPPDHNDH ECCERVVINI AGLRFETQLK TLSQFPETLL
     GNPKKRMRYF DPLRNEYFFD RNRPSFDAIL YYYQSGGRLR RPVNVPLDMF SEEIKFYELG
     VDAMERFRED EGFIREEERP LPEKEFQRQM WLLFEHPESS NTARGIAIVS VMVILISIVI
     FCLETLPQLK VDSTGHFYSV GNSTFYYKPN IFTDPFFVIE TLCIIWFSFE LIVRFLACPS
     KPAFFKNMMN TIDIVAIIPY FITLGTELAE DPNKEAVGEQ ATSLAILRVI RLVRVFRIFK
     LSRHSKGLQI LGQTLKASMR ELGLLIFFLF IGVILFSSAV YFAEVEDGGS FVSIPDAFWW
     AVVSMTTVGY GDMVPVTIGG KIVGSLCAIA GVLTIALPVP VIVSNFNYFY HRETEGEEQA
     QLLNVSTPNI PSESDLSRRS SSVVSKSEYM EIDGDINNSI DNFREANLRT GNCTIATQNC
     VNKSKLLTDV
//
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