ID H2LN03_ORYLA Unreviewed; 425 AA.
AC H2LN03;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000007426.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000007426.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000007426.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000007426.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000007426.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2LN03; -.
DR STRING; 8090.ENSORLP00000007426; -.
DR Ensembl; ENSORLT00000007427.2; ENSORLP00000007426.2; ENSORLG00000005908.2.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT01090000260059; -.
DR HOGENOM; CLU_013137_0_2_1; -.
DR InParanoid; H2LN03; -.
DR TreeFam; TF351086; -.
DR Proteomes; UP000001038; Chromosome 17.
DR Bgee; ENSORLG00000005908; Expressed in blastula and 10 other cell types or tissues.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF36; E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 22..64
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 155..195
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT COILED 197..230
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 275..302
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 425 AA; 48389 MW; D674D7F431648D10 CRC64;
MQHSVLKYDQ KRVNLNEAAF SCSICLDLLD IPVTIPCGHS YCMVCIKGFW KGKENDSRSC
PQCRETFTSA PALVKNTMLA ALTEELQKTG ICPPAAEHHY AGAEDVACDI CTGKKLHAVK
SCLTCLASYC EEHLQPHSDV AAFKKHKLVE PFKNLQETIC SIHNEVMKLF CRTDQKCICY
LCSVEEHKGH DTVSAAAERT ERQRELEENQ LQIQQRIQDR EKEVKLLQQQ EEATNMSVDQ
VVENSEKIFT DIICLIDKKK GEVKNKFRSQ QQTKVGQVKG LQEELEQEIT ELKRRDAELK
QLSLTEDHHQ FLHSYSSLPP LSGESTHSSS IIVRPPGNLK DVTAAVLELR KKLEDILREE
LTRISLTITQ VDVSPWEPKS RPDFLTYYRN LTLDPNTAHT RLMMLKKKKV IGVARTLHYT
SGKQL
//
