ID H2LU43_ORYLA Unreviewed; 468 AA.
AC H2LU43;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Zgc:123010 {ECO:0000313|Ensembl:ENSORLP00000009616.2};
GN Name=zgc:123010 {ECO:0000313|Ensembl:ENSORLP00000009616.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000009616.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000009616.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000009616.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000009616.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000009616.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2LU43; -.
DR Ensembl; ENSORLT00000009617.2; ENSORLP00000009616.2; ENSORLG00000007675.2.
DR eggNOG; KOG0548; Eukaryota.
DR GeneTree; ENSGT00940000161036; -.
DR HOGENOM; CLU_000134_46_2_1; -.
DR TreeFam; TF334582; -.
DR Proteomes; UP000001038; Chromosome 15.
DR Bgee; ENSORLG00000007675; Expressed in animal zygote and 14 other cell types or tissues.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR47678; TETRATRICOPEPTIDE REPEAT PROTEIN 31; 1.
DR PANTHER; PTHR47678:SF2; TETRATRICOPEPTIDE REPEAT PROTEIN 31 ISOFORM X1; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF07719; TPR_2; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 208..241
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 276..309
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 372..444
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 20..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..83
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..114
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 52326 MW; 350D72FC73B022C1 CRC64;
MVALMKFTRD ICRLLGLGSG SAMQPPGEQM DCSAATLDPG HDATLTQDAL NGEEDVSEEE
KLRRKVERRK AKRKRRRKKK KQEQIKKTDS AEQDDEEDCA AESELDDSES EADVVPEDEK
QAAHKEGKKE IKPTAVPTTV ISPAENKGQQ KTKTKSSEEE PEWDVSSAFF AHAVSHIKPK
GASRKSKENK ENEAKRETNG TDSMTKKSAS LTEKGIKLVQ QGEYAQAASM FTEAIKCDPK
DYRFFGNRSY CYCCLELYSQ ALADAERSIQ LDPGWPKGYF RKGNALMGLK RYSEAEKAME
QVLKLDEDCE EAENDLFYCK VQQLMELGFE ETQSIRLLES FSTVQAVLAS CSDAAKAGSQ
DPSVVQPGSP CPSLWVGNVT TELTEKHLWD LFKIYGEIES IRVLHERFCA FVNFRNANMA
ARAMEKLNGH CIENTRLVVR YPDRRAQRIL PVPLKSVPVS QQAGAAVG
//
