ID H2M8I9_ORYLA Unreviewed; 637 AA.
AC H2M8I9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor {ECO:0000313|Ensembl:ENSORLP00000014805.1};
GN Name=taf6l {ECO:0000313|Ensembl:ENSORLP00000014805.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000014805.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000014805.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000014805.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000014805.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000014805.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF6 family.
CC {ECO:0000256|ARBA:ARBA00007688}.
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DR RefSeq; XP_004080111.1; XM_004080063.1.
DR AlphaFoldDB; H2M8I9; -.
DR STRING; 8090.ENSORLP00000014805; -.
DR Ensembl; ENSORLT00000014806.2; ENSORLP00000014805.1; ENSORLG00000011816.2.
DR GeneID; 101170624; -.
DR KEGG; ola:101170624; -.
DR CTD; 10629; -.
DR eggNOG; KOG2549; Eukaryota.
DR GeneTree; ENSGT00640000091486; -.
DR HOGENOM; CLU_022764_0_0_1; -.
DR InParanoid; H2M8I9; -.
DR OMA; YYQHVTR; -.
DR OrthoDB; 3014558at2759; -.
DR TreeFam; TF328731; -.
DR Proteomes; UP000001038; Chromosome 18.
DR Bgee; ENSORLG00000011816; Expressed in ovary and 14 other cell types or tissues.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR CDD; cd08050; TAF6C; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037796; TAF6.
DR InterPro; IPR011442; TAF6_C.
DR InterPro; IPR046344; TAF6_C_sf.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10221:SF22; TAF6-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 6L; 1.
DR PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR Pfam; PF02969; TAF; 1.
DR Pfam; PF07571; TAF6_C; 1.
DR SMART; SM00803; TAF; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..73
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|SMART:SM00803"
FT REGION 480..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 69536 MW; 61B678CF36F350AA CRC64;
MAEREERRFA QVSRESVALM AESAGVELGE EMAAVLAEDV CYRLREAAQS CSQFMKHAKR
KKLTVEDFNR ALRWSNVEAV CGYGAQDALP FRSGKEGELF FVDDREINLI ELALATNIPK
GCAETMVRVN VAYLDGKGGV ELQGAVPTAV QSLSDDLLKY YQQITRAILG DDPHLMKVAL
LDLQSNSKIA ALLPYFVYVI SGVKSVSHDL EQLNRLLHMV RSLVQNPYLY LGSYVRSLVS
SVMYCILEPL AASINPLNDH WTLRDYAALL LSNIFWTHGD LVSGLYHQIL LSLQKVLSDP
VRPLCSHYGA VVGLHALGWK AVEKVLFPHL PAYWANLQAV LDDYSVSNAQ VKADGHKVYG
AILVAVERLL KMKALSLSHP GEWCFNAQTG SLAAAVGYSS PGLSPPPESL SEAAFGIASH
LQAGSGGCPW EEWAPVSLPA MYLELYSFFG DSLAVRFSTG PGLDSPPYCP SALLREPKKE
ALGQGSNSDT ARKMPQLTAN LSISPRRDGS PRTDPPPPSL AAAGPGRSLP RSSSAQRSRY
SSSRSAQRLT GLPRDVFPKA RFASPQNGPP TFSFVIGGRQ MGQRCQGRRP FQTVFAPTPP
PAAVPPRAYA HKLPVIGRVG KPVRRWTCSH YSLLLPL
//
