ID   H2MJT0_ORYLA            Unreviewed;       589 AA.
AC   H2MJT0;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 2.
DT   27-MAR-2024, entry version 74.
DE   RecName: Full=Neurofibromin 1b {ECO:0008006|Google:ProtNLM};
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000018929.2, ECO:0000313|Proteomes:UP000001038};
RN   [1] {ECO:0000313|Ensembl:ENSORLP00000018929.2, ECO:0000313|Proteomes:UP000001038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000018929.2,
RC   ECO:0000313|Proteomes:UP000001038};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA   Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA   Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA   Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA   Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA   Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSORLP00000018929.2}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000018929.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; H2MJT0; -.
DR   STRING; 8090.ENSORLP00000018929; -.
DR   Ensembl; ENSORLT00000018930.2; ENSORLP00000018929.2; ENSORLG00000015104.2.
DR   eggNOG; KOG1826; Eukaryota.
DR   GeneTree; ENSGT00550000074797; -.
DR   HOGENOM; CLU_000249_0_0_1; -.
DR   InParanoid; H2MJT0; -.
DR   TreeFam; TF300302; -.
DR   Proteomes; UP000001038; Chromosome 13.
DR   Bgee; ENSORLG00000015104; Expressed in brain and 14 other cell types or tissues.
DR   GO; GO:0070966; P:nuclear-transcribed mRNA catabolic process, no-go decay; IEA:InterPro.
DR   GO; GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IEA:InterPro.
DR   GO; GO:0071025; P:RNA surveillance; IEA:InterPro.
DR   InterPro; IPR004405; Transl-rel_pelota.
DR   PANTHER; PTHR10853; PELOTA; 1.
DR   PANTHER; PTHR10853:SF0; PROTEIN PELOTA HOMOLOG; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT   REGION          498..519
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          534..589
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        534..579
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   589 AA;  65881 MW;  01529143594F8449 CRC64;
     MRDIPSCKWL DQWTELAQKF AFQYNPSLQP RALVVFGCIS KRVTHSQIKQ IIRILSKGLE
     SCLKGPDNYN SQVLIEATVI ALTKLQPLLS KDSPMHKALF WVAVAVLQLD EVNLYSAGTA
     LLEQNLHTLD TMRVFNDKSP EEVFMEIRCP LEWHCKQMDH FVGLNFGANF NFALVGHLLK
     GYRHPSPTTV ARTVRILHTL LSLISKHLKC DKFEVNTQSV AYLAALLTVS EEVRSRCSLK
     HRKSLLISDL SMDPVPMDTY SSHIPDATCR TLHEPQPWPS PQVSDRCYLS AHQYSTVGQI
     SPRTRKSMSL DMGQPSQANT KKLLGKGLPH SSGKTQRIGN SHLRKVSVSE SNVLLDEEVL
     TDPKIQALLL TVLATQVKYS TDDFDQRILY EYLAEASVVF PKVFPVVYNL LDSKINTVLT
     MCQDTNLLNP VHGIVQSVVY HEESPPQYQP SYLQSFGFNG LWRFAGPFSK QTQIPDYAEL
     IVKFLEALID SYLPAADEER GEEQLRTPTS PYPPSSQSQL SITANLNLSN SMTSLATSQH
     SPGVDKENVQ LSPSSALSSG GRTRHGSASQ VQKQRSAGSF KRPSIKKMV
//