ID   H2NKY7_PONAB            Unreviewed;       575 AA.
AC   H2NKY7; A0A2J8THW0;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 3.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=SCFD1 isoform 3 {ECO:0000313|EMBL:PNJ32611.1};
DE   SubName: Full=Sec1 family domain containing 1 {ECO:0000313|Ensembl:ENSPPYP00000006502.3};
GN   Name=SCFD1 {ECO:0000313|Ensembl:ENSPPYP00000006502.3};
GN   ORFNames=CR201_G0034798 {ECO:0000313|EMBL:PNJ32611.1};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000006502.3, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000006502.3, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PNJ32611.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Susie {ECO:0000313|EMBL:PNJ32611.1};
RA   Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA   Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA   Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA   Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA   Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT   "High-resolution comparative analysis of great ape genomes.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPPYP00000006502.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC       {ECO:0000256|ARBA:ARBA00009884}.
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DR   EMBL; NDHI03003497; PNJ32611.1; -; Genomic_DNA.
DR   Ensembl; ENSPPYT00000006758.3; ENSPPYP00000006502.3; ENSPPYG00000005720.3.
DR   eggNOG; KOG1301; Eukaryota.
DR   GeneTree; ENSGT00550000074845; -.
DR   HOGENOM; CLU_016216_3_1_1; -.
DR   OMA; VNDLRAW; -.
DR   TreeFam; TF105740; -.
DR   Proteomes; UP000001595; Chromosome 14.
DR   GO; GO:0005801; C:cis-Golgi network; IEA:Ensembl.
DR   GO; GO:1902902; P:negative regulation of autophagosome assembly; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0051223; P:regulation of protein transport; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.40.60; -; 1.
DR   Gene3D; 3.40.50.1910; -; 1.
DR   Gene3D; 3.40.50.2060; -; 1.
DR   InterPro; IPR043154; Sec-1-like_dom1.
DR   InterPro; IPR043127; Sec-1-like_dom3a.
DR   InterPro; IPR001619; Sec1-like.
DR   InterPro; IPR027482; Sec1-like_dom2.
DR   InterPro; IPR036045; Sec1-like_sf.
DR   PANTHER; PTHR11679:SF2; SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR   Pfam; PF00995; Sec1; 1.
DR   PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR   SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
SQ   SEQUENCE   575 AA;  65061 MW;  D661C294F7170C05 CRC64;
     MGITLHLLLH SDRDPIPDVP AVYFVMPTEE NIDRMCQDLR NQLYESYYLN FISAISRSKL
     EDIANAALAA SAVTQVAKVF DQYLNFITLE DDMFVLCNQN KELVSYRAIN RPDITDTEME
     TVMDTIVDSL FCFFVTLGAV PIIRCSRGTA AEMVAVKLDK KLRENLRDAR NSLFTGDTLG
     AGQFSFQRPL LVLVDRNIDL ATPLHHTWTY QALVHDVLDF HLNRVNLEES SGVENSPAGA
     RPKRKNKKSY DLTPVDKFWQ KHKGSPFPEV AESVQQELES YRAQEDEVKR LKSIMGLEGE
     DEGAISMLSD NTAKLTSAVS SLPELLEKKR LIDLHTNVAT AVLEHIKARK LDVYFEYEEK
     IMSKTTLDKS LLDIISDPDA GTPEDKMRLF LIYYISTQQA PSEADLEQYK KALTDAGCNL
     NPLQYIKQWK AFTKMASAPA SYGSTTTKPM GLLSRVMNTG SQFVMEGVKN LVLKQQNLPV
     TRILDNLMEM KSNPETDDYR YFDPKMLRGN DSSVPRNKNP FQEAIVFVVG GGNYIEYQNL
     VDYIKGKQGK HILYGCSELF NATQFIKQLS QLGQK
//