ID H2P6X3_PONAB Unreviewed; 114 AA.
AC H2P6X3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Large ribosomal subunit protein P1 {ECO:0000256|ARBA:ARBA00041116};
DE AltName: Full=60S acidic ribosomal protein P1 {ECO:0000256|ARBA:ARBA00042918};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000014108.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000014108.2, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPPYP00000014108.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Plays an important role in the elongation step of protein
CC synthesis. {ECO:0000256|ARBA:ARBA00003362}.
CC -!- SUBUNIT: Heterodimer with RPLP2 at the lateral ribosomal stalk of the
CC large ribosomal subunit. {ECO:0000256|ARBA:ARBA00038554}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC {ECO:0000256|ARBA:ARBA00005436}.
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DR RefSeq; XP_009240471.1; XM_009242196.1.
DR AlphaFoldDB; H2P6X3; -.
DR Ensembl; ENSPPYT00000014680.2; ENSPPYP00000014108.2; ENSPPYG00000032551.1.
DR eggNOG; KOG1762; Eukaryota.
DR GeneTree; ENSGT00550000074698; -.
DR HOGENOM; CLU_114656_1_2_1; -.
DR InParanoid; H2P6X3; -.
DR OMA; NVWADVY; -.
DR TreeFam; TF312932; -.
DR Proteomes; UP000001595; Chromosome 6.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:UniProt.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006414; P:translational elongation; IEA:InterPro.
DR CDD; cd05831; Ribosomal_P1; 1.
DR Gene3D; 1.10.10.1410; -; 1.
DR HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR InterPro; IPR038716; P1/P2_N_sf.
DR InterPro; IPR027534; Ribosomal_P1/P2.
DR PANTHER; PTHR45696; 60S ACIDIC RIBOSOMAL PROTEIN P1; 1.
DR PANTHER; PTHR45696:SF10; 60S ACIDIC RIBOSOMAL PROTEIN P1-RELATED; 1.
DR Pfam; PF00428; Ribosomal_60s; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980}.
FT REGION 68..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..104
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 114 AA; 11485 MW; 4228C4AF01F8BB78 CRC64;
MASVSELACI YSALILHNDE VTVTEDKINA LIKAAGVNVE PFWPGLFAKA LANVNIGSLI
CNAGAGGPAP AAGAAPAGGP APSTAAAPAE EKKVEAKKEE SEESDDDMGF GLFD
//
