ID H2PBG4_PONAB Unreviewed; 415 AA.
AC H2PBG4; A0A2J8U3I7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=BFSP2 isoform 3 {ECO:0000313|EMBL:PNJ39827.1};
DE SubName: Full=Beaded filament structural protein 2 {ECO:0000313|Ensembl:ENSPPYP00000015787.2};
GN Name=BFSP2 {ECO:0000313|Ensembl:ENSPPYP00000015787.2};
GN ORFNames=CR201_G0030497 {ECO:0000313|EMBL:PNJ39827.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000015787.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000015787.2, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ39827.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ39827.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000015787.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003471; PNJ39827.1; -; Genomic_DNA.
DR RefSeq; XP_002814103.1; XM_002814057.3.
DR STRING; 9601.ENSPPYP00000015787; -.
DR Ensembl; ENSPPYT00000016409.2; ENSPPYP00000015787.2; ENSPPYG00000014110.2.
DR GeneID; 100441274; -.
DR KEGG; pon:100441274; -.
DR CTD; 8419; -.
DR eggNOG; ENOG502QTD1; Eukaryota.
DR GeneTree; ENSGT00940000159820; -.
DR HOGENOM; CLU_012560_0_0_1; -.
DR OMA; ETIRIQW; -.
DR OrthoDB; 4223979at2759; -.
DR TreeFam; TF332742; -.
DR Proteomes; UP000001595; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005212; F:structural constituent of eye lens; IEA:Ensembl.
DR GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
DR GO; GO:0070307; P:lens fiber cell development; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF32; PHAKININ; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT DOMAIN 104..415
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 199..240
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 314..394
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 45844 MW; DFC5C51D8DFECE9B CRC64;
MSERRVVVDL PTSASSSMPL QRRRASFRGP RSSSSLDSPP ASRTNAMTGL VRAPGVYVGT
APSGCIGGLG ARVTRRALGI SSVFLQGLRS SGLATVPAPG LERDHGAVED LGGCLVEYMA
KVHALEQVSQ ELETQLRMHL ESKATRSGNW GALRASWASS CQQVGEAVLE NARLMLQTET
IQAGADDFKE RYENELPFRK AAEEEINSLY KVIDEANLTK MDLESQIESL KEEFGSLSRN
YEEDVKVLHK QLAGCELEQM DVPIGTGLDD ILETIRIQWE RDVEKNRVEA GALLQAKQQA
EVAHMSQTQE EKLAAALRVE LHNTSCQVQS LQAETESLRA LKRGLENTLH DAKHWHDMEL
QNLGAVVGRL EAELSEIRAE AEQQQQERAH LLARKCQLQK DVASYHALLD REESG
//
