ID H2PNC6_PONAB Unreviewed; 595 AA.
AC H2PNC6; A0A2J8U4X4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=SLC13A1 isoform 1 {ECO:0000313|EMBL:PNJ40327.1};
DE SubName: Full=Solute carrier family 13 member 1 {ECO:0000313|Ensembl:ENSPPYP00000020137.3};
GN Name=DKFZP469N2120 {ECO:0000313|Ensembl:ENSPPYP00000020137.3};
GN ORFNames=CR201_G0030478 {ECO:0000313|EMBL:PNJ40327.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000020137.3, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000020137.3, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ40327.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ40327.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000020137.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
CC NADC subfamily. {ECO:0000256|ARBA:ARBA00006772}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NDHI03003470; PNJ40327.1; -; Genomic_DNA.
DR STRING; 9601.ENSPPYP00000020137; -.
DR Ensembl; ENSPPYT00000020929.3; ENSPPYP00000020137.3; ENSPPYG00000017954.3.
DR eggNOG; KOG1281; Eukaryota.
DR GeneTree; ENSGT01030000234550; -.
DR HOGENOM; CLU_005170_9_1_1; -.
DR OMA; THIMAHT; -.
DR OrthoDB; 1359392at2759; -.
DR TreeFam; TF312913; -.
DR Proteomes; UP000001595; Chromosome 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015382; F:sodium:sulfate symporter activity; IEA:Ensembl.
DR CDD; cd01115; SLC13_permease; 1.
DR InterPro; IPR031312; Na/sul_symport_CS.
DR InterPro; IPR001898; SLC13A/DASS.
DR PANTHER; PTHR10283; SOLUTE CARRIER FAMILY 13 MEMBER; 1.
DR PANTHER; PTHR10283:SF65; SOLUTE CARRIER FAMILY 13 MEMBER 1; 1.
DR Pfam; PF00939; Na_sulph_symp; 1.
DR PROSITE; PS01271; NA_SULFATE; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023201};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Sodium {ECO:0000256|ARBA:ARBA00023201};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..532
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 595 AA; 66034 MW; EB98EBDDC053A596 CRC64;
MKFFSYILVY RRFLLVVFTV LVLLPLPIVL HNKEAECAYT LFVVATFWLT EALPLSVTAL
LPSLMLPMFG IMPSKKVASA YFKDFHLLLI GVICLATSIE KWNLHKRIAL KMVMMVGVNP
AWLTLGFMSS TAFLSMWLSN TSTAAMVMPI AEAVAQQIIN AEAEVEATQM TYFNGSTNHG
LEIDESVNGH EINERKEKTK PVPGYNNDTG KISSKVELEK TSGMGTKYRT KKGHMTCKLM
CLCIAYSSTI GGLTTITGTS TNLIFAEYFN TRYPDCRCLN FGSWFTFSFP AALIILLLSW
IWLQWFFLGF NFKETFKCGK TKIVQQKACA EVIKQEYQKL GPIRYQEIVT LVLFIIMALL
WFSRDPGFVP GWSALFSEYP GFATDSTVAL LIGLLFFLIP AKRLTETTPT GEIVAFDYSP
LITWKEFQSF MPWDIAILVG GGFALADGCE ESGLSKWIGN KLSPLGSLPI WLIILISSLM
VTSLTEVASN PATITVVLPI LSPLAEAIHV NPLYILIPST LCTSFAFLLP VANPPNAIVF
SYGHLKVIDM VKAGLGVNIV GVAVVMLGIC TWIVPMFDLY TYPSWAPAMS NETMP
//
