ID H2Q2D3_PANTR Unreviewed; 67 AA.
AC H2Q2D3; A0A2J8PDM6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=MORN repeat-containing protein 4 {ECO:0000256|ARBA:ARBA00039855};
GN Name=MORN4 {ECO:0000313|Ensembl:ENSPTRP00000004935.4,
GN ECO:0000313|VGNC:VGNC:57524};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000004935.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000004935.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000004935.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Plays a role in promoting axonal degeneration following
CC neuronal injury by toxic insult or trauma.
CC {ECO:0000256|ARBA:ARBA00037780}.
CC -!- SUBUNIT: Interacts with MYO3A. {ECO:0000256|ARBA:ARBA00038723}.
CC -!- SUBCELLULAR LOCATION: Cell projection, filopodium tip
CC {ECO:0000256|ARBA:ARBA00004495}. Cell projection, stereocilium
CC {ECO:0000256|ARBA:ARBA00004645}.
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DR EMBL; AACZ04051087; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2Q2D3; -.
DR Ensembl; ENSPTRT00000005333.4; ENSPTRP00000004935.4; ENSPTRG00000045678.1.
DR VGNC; VGNC:57524; MORN4.
DR eggNOG; KOG0231; Eukaryota.
DR GeneTree; ENSGT00730000111173; -.
DR HOGENOM; CLU_116793_0_0_1; -.
DR TreeFam; TF323893; -.
DR Proteomes; UP000002277; Chromosome 10.
DR Bgee; ENSPTRG00000045678; Expressed in prefrontal cortex and 17 other cell types or tissues.
DR GO; GO:0032433; C:filopodium tip; IEA:UniProtKB-SubCell.
DR GO; GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
DR InterPro; IPR003409; MORN.
DR PANTHER; PTHR46614; MORN REPEAT-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46614:SF1; MORN REPEAT-CONTAINING PROTEIN 4; 1.
DR Pfam; PF02493; MORN; 2.
DR SMART; SM00698; MORN; 2.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 67 AA; 7476 MW; BC2C013D6BB986C9 CRC64;
MTLTKGSFTY SSGEEYRGEW KEGRRHGFGQ LMFADGGTYL GHFENGLFNG FGVLTFSDGS
RPADFPR
//
