ID H2Q393_PANTR Unreviewed; 122 AA.
AC H2Q393;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Serum amyloid A protein {ECO:0000256|RuleBase:RU000539};
GN Name=SAA2 {ECO:0000313|Ensembl:ENSPTRP00000005953.2,
GN ECO:0000313|VGNC:VGNC:1010};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000005953.2, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000005953.2, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000005953.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Major acute phase reactant. Apolipoprotein of the HDL
CC complex. {ECO:0000256|RuleBase:RU000539}.
CC -!- SIMILARITY: Belongs to the SAA family. {ECO:0000256|ARBA:ARBA00007745,
CC ECO:0000256|RuleBase:RU000539}.
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DR EMBL; AACZ04016566; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_001173019.1; XM_001173019.4.
DR RefSeq; XP_003312991.1; XM_003312943.3.
DR AlphaFoldDB; H2Q393; -.
DR PaxDb; 9598-ENSPTRP00000005953; -.
DR Ensembl; ENSPTRT00000006453.3; ENSPTRP00000005953.2; ENSPTRG00000003416.3.
DR GeneID; 748829; -.
DR KEGG; ptr:748829; -.
DR CTD; 6289; -.
DR VGNC; VGNC:1010; SAA2.
DR eggNOG; ENOG502S4PB; Eukaryota.
DR GeneTree; ENSGT00390000004737; -.
DR HOGENOM; CLU_129936_0_0_1; -.
DR InParanoid; H2Q393; -.
DR OMA; KGAGDMW; -.
DR OrthoDB; 2958429at2759; -.
DR TreeFam; TF332544; -.
DR Proteomes; UP000002277; Chromosome 11.
DR Bgee; ENSPTRG00000003416; Expressed in liver and 13 other cell types or tissues.
DR GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-UniRule.
DR GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.132.110; Serum amyloid A protein; 1.
DR InterPro; IPR000096; Serum_amyloid_A.
DR Pfam; PF00277; SAA; 1.
DR PIRSF; PIRSF002472; Serum_amyloid_A; 1.
DR PRINTS; PR00306; SERUMAMYLOID.
DR SMART; SM00197; SAA; 1.
DR PROSITE; PS00992; SAA; 1.
PE 3: Inferred from homology;
KW Acute phase {ECO:0000256|ARBA:ARBA00022486, ECO:0000256|RuleBase:RU000539};
KW HDL {ECO:0000256|ARBA:ARBA00022850, ECO:0000256|RuleBase:RU000539};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..122
FT /note="Serum amyloid A protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003569711"
FT REGION 90..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 122 AA; 13478 MW; D913BF1F41F99AFD CRC64;
MKLLTGLVFC SLVLGVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY
DAAKRGPGGA WAAEVISNAR ENIQRLTGHG AEDSLADQAA NKWGRSGRDP NHFRPAGLPE
KY
//
