ID H2Q400_PANTR Unreviewed; 1476 AA.
AC H2Q400;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Coiled-coil domain containing 88B {ECO:0000313|Ensembl:ENSPTRP00000006602.4};
GN Name=CCDC88B {ECO:0000313|Ensembl:ENSPTRP00000006602.4,
GN ECO:0000313|VGNC:VGNC:3162};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000006602.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000006602.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000006602.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC175468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPTRT00000007155.4; ENSPTRP00000006602.4; ENSPTRG00000003836.6.
DR VGNC; VGNC:3162; CCDC88B.
DR eggNOG; KOG4643; Eukaryota.
DR GeneTree; ENSGT00940000162048; -.
DR HOGENOM; CLU_002567_1_0_1; -.
DR TreeFam; TF320231; -.
DR Proteomes; UP000002277; Chromosome 11.
DR Bgee; ENSPTRG00000003836; Expressed in lymph node and 16 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR CDD; cd22230; HkD_Gipie; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR043936; HOOK_N.
DR PANTHER; PTHR18947:SF35; COILED-COIL DOMAIN-CONTAINING PROTEIN 88B; 1.
DR PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR Pfam; PF19047; HOOK_N; 1.
DR SUPFAM; SSF116907; Hook domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1476
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019291995"
FT DOMAIN 56..177
FT /note="HOOK N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19047"
FT REGION 427..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 825..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1323..1476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 253..425
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 454..481
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 987..1298
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 570..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1399..1415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1447..1465
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1476 AA; 164509 MW; 4C782BD58C3F25DF CRC64;
MEGGKGPRLR DFLSGSLATW ALGLAGLVGE AEDSEGEEEE EEEEPPLWLE KRFLRLSDGA
LLLRVLGIIA PSSRGGPRML RGLDGPAAWR VWNLNRLWGR LRDFYQEELQ LLILSPPPDL
QTLGFDPLSE EAVEQLEGVL RLLLGASVQC EHRELFIRHI QGLSLEVQSE LAAAIQEVTQ
PGAGVVLALS GPEPGDLAPA ELEMLSRSLM GTLSKLARER DLGAQRLAEL LLEREPLCLG
PQAPSRAPAE GPSHHLALQL ANAKAQLRRL RQELEEKAEL LLDSQAEVQG LEAEIRRLRQ
EAQALSGQAK RAELYREEAE ALRERAGRLP RLQEELRRCR ERLQAAEAYK SQLEEERVLS
GVLEASKALL EEQLEAARER CARLHETQRE NLLLRTRLGE AHAELDSLRH QVDQLAEENV
ELELELQRSL EPPPGSPGEA PLAGAAPSLQ DEVREAEAGR LRTLERENRE LRGLLQVLQG
QPGGQHPLLE APREDPVLPV LEEAPQTPVA SDHSPQGLVQ KARDGGPQAL DLAPLALDSV
LEASAECPQA PDSDPQEAES PLQAAAMDPQ ASDWSPQESG SPVETQESPE KAGRRSSLQS
PASVAPPQGP GTKIQAPQLL GGETEGREAP QGELVPEARG LRQEGPEHKP GPSEPSSVQL
EEQEGPNQGL DLATGQAEAR EHDQRLEGTV RVPAWQKPQQ KSEGALEVQV WEGPIPGESL
ASGVAEQEAL REEVAQLRRK AEALGDELEA QACKLEAQNT EAARLSKELA QARRAEAEAH
REAEAKAWEQ ARLREAVEAA GRELESASQE REALVEALAA AGRERRQWER EGSRLRAQSE
AAEERMQVLE SEGRQHLEEA ERERREKEAL QAELEKAVVR GKELGARLEH LQRELEQAAL
ERQEFLREKE SQHQRYQGLE QRLEAELQAA ATSKEEALME LKTRALQLEE ELFQLRQGPA
GLGPKKRAEP QLVETQNVRL IEVERSNAML VAEKAALQGQ LQHLEGQLGS LQGRAQELLL
QSQRAQEHSS RLQAEKSVLE IQGQELHRKL EVLEEEVRAA RQSQEETRGQ QQALLRDHEA
LAQLQRRQEA ELEGLLVRHR DLKANMRALE LAHRELQGRH EQLQAQRASV EAQEVALLAE
RERLMQDGHR QRGLEEELRR LQSEHDRAQM LLAEVSRERG ELQGERGELR GRLARLELER
AQLEMQSQQL RESNQQLDLS ACRLTTQCEL LTQLRSAQEE ENRQLLAEVQ ALSRENRELL
ERSLESRDHL HREQREYLDQ LNALRREKQK LVEKIMDQYR VLEPVPLPRT KKGSWLADKV
KRLMRPRREG GPPGGLRLGA DGAGSTESLG GPPETELPEG READGTGSPS PAPMRRAQSS
LCLRDETLAG GQRRKLSSRF PVGRSSESFS PGDTPRQRFR QRHPGPLGAP VSHSKGPGVG
WENSAETLQE HETDANREGP EAQEPEKHPL TPSLSQ
//
