ID H2Q430_PANTR Unreviewed; 288 AA.
AC H2Q430; A0A2J8QC33;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Solute carrier family 25 member 45 {ECO:0000313|Ensembl:ENSPTRP00000006677.4};
DE SubName: Full=Solute carrier family 25, member 45 {ECO:0000313|EMBL:JAA11488.1};
GN Name=SLC25A45 {ECO:0000313|EMBL:JAA11488.1,
GN ECO:0000313|Ensembl:ENSPTRP00000006677.4, ECO:0000313|VGNC:VGNC:7750};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000006677.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000006677.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA11488.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skin {ECO:0000313|EMBL:JAA25988.1}, and Smooth vascular
RC {ECO:0000313|EMBL:JAA11488.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000006677.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; AACZ04016217; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABF01010657; JAA11488.1; -; mRNA.
DR EMBL; GABD01007112; JAA25988.1; -; mRNA.
DR RefSeq; XP_016776725.1; XM_016921236.1.
DR RefSeq; XP_508552.2; XM_508552.5.
DR STRING; 9598.ENSPTRP00000006677; -.
DR PaxDb; 9598-ENSPTRP00000006677; -.
DR Ensembl; ENSPTRT00000007240.5; ENSPTRP00000006677.4; ENSPTRG00000003874.7.
DR GeneID; 451322; -.
DR CTD; 283130; -.
DR VGNC; VGNC:7750; SLC25A45.
DR eggNOG; KOG0758; Eukaryota.
DR GeneTree; ENSGT00940000161002; -.
DR HOGENOM; CLU_015166_16_1_1; -.
DR OMA; QLFAGGC; -.
DR OrthoDB; 4064096at2759; -.
DR TreeFam; TF351739; -.
DR Proteomes; UP000002277; Chromosome 11.
DR Bgee; ENSPTRG00000003874; Expressed in hindlimb stylopod muscle and 18 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45624; MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR45624:SF6; SOLUTE CARRIER FAMILY 25 MEMBER 45; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT TRANSMEM 55..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 1..83
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 97..191
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 199..286
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 288 AA; 31830 MW; AE4391DBD8C6AF09 CRC64;
MPVEEFVAGW ISGALGLVLG HPFDTVKVRL QTQTTYRGIV DCMVKIYRHE SLLGFFKGMS
FPIASIAVVN SVLFGVYSNT LLVLTATSHQ ERRAQPPSYT HIFLAGCTGG FLQAYCLAPF
DLIKVRLQNQ TEPRAQPGSP PPRYQGPVHC AASIFREEGP RGLFRGAWAL TLRDTPTVGI
YFITYEGLCR QYTPEGQNPS SATVLVAGGF AGIASWVAAT PLDVIKSRMQ MDGLRRRVYQ
GMLDCMVSSV RQEGLGVFFR GVTINSARAF PVNAVTFLSY EYLLRWWG
//
