ID H2QA57_PANTR Unreviewed; 252 AA.
AC H2QA57;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Ankyrin repeat and SOCS box containing 7 {ECO:0000313|Ensembl:ENSPTRP00000012822.6};
GN Name=ASB7 {ECO:0000313|Ensembl:ENSPTRP00000012822.6,
GN ECO:0000313|VGNC:VGNC:11822};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000012822.6, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000012822.6, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000012822.6}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR EMBL; AACZ04059922; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04059923; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2QA57; -.
DR Ensembl; ENSPTRT00000013835.6; ENSPTRP00000012822.6; ENSPTRG00000007507.6.
DR VGNC; VGNC:11822; ASB7.
DR eggNOG; KOG4177; Eukaryota.
DR GeneTree; ENSGT00940000158068; -.
DR HOGENOM; CLU_084795_0_0_1; -.
DR TreeFam; TF331695; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000002277; Chromosome 15.
DR Bgee; ENSPTRG00000007507; Expressed in lymph node and 21 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03726; SOCS_ASB7; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037326; ASB7_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24189; MYOTROPHIN; 1.
DR PANTHER; PTHR24189:SF50; MYOTROPHIN-RELATED; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 14..46
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 50..82
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 83..115
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 147..179
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 207..247
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 252 AA; 28512 MW; EB5D312E8F1C5932 CRC64;
SPEITDPTVK DLIGGFTALH YAAMHGRARI ARLMLESEYR SDIINAKSND GWTPLHVAAH
YGRDSFVRLL LEFKAEVDPL SDKGTTPLQL AIIRERSSCV KILLDHNANI DIQNGFLLRY
AVIKSNHSYC RMFLQRGADT NLGRLEDGQT PLHLSALRDD VLCARMLYNY GADTNTRNYE
GQTPLAVSIS ISGSSRPCLD FLQEVTRQPR NLQDLCRIKI RQCIGLQNLK LLDELPIAKV
MKDYLKHKFD DI
//
