ID H2QW72_PANTR Unreviewed; 370 AA.
AC H2QW72; A0A2J8KHH9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Protein FAM110B {ECO:0000256|ARBA:ARBA00039346};
GN Name=FAM110B {ECO:0000313|EMBL:JAA37017.1,
GN ECO:0000313|Ensembl:ENSPTRP00000071310.1, ECO:0000313|VGNC:VGNC:3020};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000071310.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000071310.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA37017.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAA37017.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000071310.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
CC -!- SIMILARITY: Belongs to the FAM110 family.
CC {ECO:0000256|ARBA:ARBA00010576}.
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DR EMBL; AACZ04016038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABE01007722; JAA37017.1; -; mRNA.
DR RefSeq; XP_003311766.1; XM_003311718.3.
DR RefSeq; XP_003311767.1; XM_003311719.3.
DR RefSeq; XP_003951315.1; XM_003951266.3.
DR RefSeq; XP_009453696.1; XM_009455421.2.
DR RefSeq; XP_016814993.1; XM_016959504.1.
DR STRING; 9598.ENSPTRP00000071310; -.
DR PaxDb; 9598-ENSPTRP00000034709; -.
DR Ensembl; ENSPTRT00000107685.1; ENSPTRP00000071310.1; ENSPTRG00000044402.1.
DR GeneID; 746137; -.
DR KEGG; ptr:746137; -.
DR CTD; 90362; -.
DR VGNC; VGNC:3020; FAM110B.
DR eggNOG; ENOG502R37V; Eukaryota.
DR GeneTree; ENSGT00950000183056; -.
DR HOGENOM; CLU_050540_0_0_1; -.
DR OMA; IASMKSP; -.
DR OrthoDB; 5407076at2759; -.
DR TreeFam; TF330964; -.
DR Proteomes; UP000002277; Chromosome 8.
DR Bgee; ENSPTRG00000044402; Expressed in cerebellum and 19 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR InterPro; IPR025740; FAM110.
DR InterPro; IPR025741; FAM110_C.
DR InterPro; IPR025739; FAM110_N.
DR PANTHER; PTHR14758; AGAP005440-PA; 1.
DR PANTHER; PTHR14758:SF2; PROTEIN FAM110B; 1.
DR Pfam; PF14160; FAM110_C; 1.
DR Pfam; PF14161; FAM110_N; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 14..118
FT /note="Centrosome-associated FAM110 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14161"
FT DOMAIN 253..361
FT /note="Centrosome-associated FAM110 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14160"
FT REGION 127..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 370 AA; 40659 MW; 8890AD8FB6AF29EF CRC64;
MPTETLQTGS MVKPVSPAGT FTSAVPLRIL NKGPDYFRRQ AEPNPKRLSA VERLEADKAK
YVKSQEVINA KQEPVKPAVL AKPPVCPAAK RALGSPTLKV FGNHAKTESG VQRENLKLEI
LKNIINSSEG SSSGSGHKHS SRNWPPHRSE ATDLHRHSFA ESLKVYPTQG RSSPQEGGSH
VGRRLLEQSA ESFLHVSHSS SDIRKVTSVK PLKAIPCSSS APPLPPKPKI AAIASMKSPE
ADPVEPACGV SRRPSLQRSK SDLSDRYFRV DADVERFFNY CGLDPEELEN LGMENFARAN
SDIISLNFRS ASMISSDCEQ SQDSNSDLRN DDSANDRVPY GISAIERNAR IIKWLYSIKQ
ARESQKVSHV
//
