ID H2R0M4_PANTR Unreviewed; 179 AA.
AC H2R0M4; A0A2J8PPG4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=ADP ribosylation factor like GTPase 5A {ECO:0000313|Ensembl:ENSPTRP00000040936.2};
DE SubName: Full=ADP-ribosylation factor-like 5A {ECO:0000313|EMBL:JAA03294.1};
GN Name=ARL5A {ECO:0000313|EMBL:JAA03294.1,
GN ECO:0000313|Ensembl:ENSPTRP00000040936.2, ECO:0000313|VGNC:VGNC:77};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000040936.2, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000040936.2, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA03294.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA03294.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA41538.1}, Skin {ECO:0000313|EMBL:JAA28247.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA18976.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000040936.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|RuleBase:RU003925}.
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DR EMBL; AACZ04058393; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04058394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04058395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01008044; JAA03294.1; -; mRNA.
DR EMBL; GABF01003169; JAA18976.1; -; mRNA.
DR EMBL; GABD01004853; JAA28247.1; -; mRNA.
DR EMBL; GABE01003201; JAA41538.1; -; mRNA.
DR RefSeq; XP_001136344.2; XM_001136344.4.
DR STRING; 9598.ENSPTRP00000040936; -.
DR PaxDb; 9598-ENSPTRP00000040936; -.
DR Ensembl; ENSPTRT00000050898.3; ENSPTRP00000040936.2; ENSPTRG00000012538.4.
DR GeneID; 736445; -.
DR KEGG; ptr:736445; -.
DR CTD; 26225; -.
DR VGNC; VGNC:77; ARL5A.
DR eggNOG; KOG0070; Eukaryota.
DR GeneTree; ENSGT00940000154714; -.
DR HOGENOM; CLU_040729_9_1_1; -.
DR OMA; FTCWDLG; -.
DR OrthoDB; 5349301at2759; -.
DR TreeFam; TF105465; -.
DR Proteomes; UP000002277; Chromosome 2B.
DR Bgee; ENSPTRG00000012538; Expressed in skeletal muscle tissue and 21 other cell types or tissues.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:1903292; P:protein localization to Golgi membrane; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR CDD; cd04153; Arl5_Arl8; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR11711; ADP RIBOSYLATION FACTOR-RELATED; 1.
DR PANTHER; PTHR11711:SF147; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5A; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
PE 2: Evidence at transcript level;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003925};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003925};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
SQ SEQUENCE 179 AA; 20728 MW; 431CC65F8D8CB9D5 CRC64;
MGILFTRIWR LFNHQEHKVI IVGLDNAGKT TILYQFSMNE VVHTSPTIGS NVEEIVINNT
RFLMWDIGGQ ESLRSSWNTY YTNTEFVIVV VDSTDRERIS VTREELYKML AHEDLRKAGL
LIFANKQDVK ECMTVAEISQ FLKLTSIKDH QWHIQACCAL TGEGLCQGLE WMMSRLKIR
//
