ID H2R0Y7_PANTR Unreviewed; 585 AA.
AC H2R0Y7; A0A2J8MIE2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Kelch like family member 28 {ECO:0000313|Ensembl:ENSPTRP00000041466.6};
GN Name=KLHL28 {ECO:0000313|Ensembl:ENSPTRP00000041466.6,
GN ECO:0000313|VGNC:VGNC:3398};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000041466.6, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000041466.6, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000041466.6}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04059558; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_016781520.1; XM_016926031.1.
DR RefSeq; XP_016781521.1; XM_016926032.1.
DR AlphaFoldDB; H2R0Y7; -.
DR STRING; 9598.ENSPTRP00000041466; -.
DR PaxDb; 9598-ENSPTRP00000041466; -.
DR Ensembl; ENSPTRT00000043040.6; ENSPTRP00000041466.6; ENSPTRG00000022780.6.
DR GeneID; 452881; -.
DR KEGG; ptr:452881; -.
DR CTD; 54813; -.
DR VGNC; VGNC:3398; KLHL28.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000158586; -.
DR HOGENOM; CLU_004253_14_2_1; -.
DR InParanoid; H2R0Y7; -.
DR OMA; IATHMCQ; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000002277; Chromosome 14.
DR Bgee; ENSPTRG00000022780; Expressed in thymus and 21 other cell types or tissues.
DR CDD; cd18467; BACK_KLHL28_BTBD5; 1.
DR CDD; cd18257; BTB_POZ_KLHL28_BTBD5; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 49..116
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 585 AA; 65981 MW; EB305C3194DD0126 CRC64;
MHFKCKYSYP ALYQMDHTSP TYMLANLTHL HSEQLLQGLN LLRQHHELCD IILRVGDVKI
HAHKVVLASV SPYFKAMFTG NLSEKENSEV EFQCIDETAL QAIVEYAYTG TVFISQDTVE
SLLPAANLLQ IKLVLKECCA FLESQLDPGN CIGISRFAET YGCRDLYLAA TKYICQNFEA
VCQTEEFFEL THADLDEIVS NDCLNVATEE TVFYALESWI KYDVQERQKY LARLLNSVRL
PLLSVKFLTR LYEANHLIRD DRTCKHLLNE ALKYHFMPEH RLSHQTVLMT RPRCAPKVLC
AVGGKSGLFA CLDSVEMYFP QNDSWIGLAP LNIPRYEFGI CVLDQKVYVI GGIATNVRPG
VTIRKHENSV ECWNPDTNTW TSLERMNESR STLGVVVLAG ELYALGGYDG QSYLQSVEKY
IPKIRKWQPV APMTTTRSCF AAAVLDGMIY AIGGYGPAHM NSVERYDPSK DSWEMVASMA
DKRIHFGVGV MLGFIFVVGG HNGVSHLSSI ERYDPHQNQW TVCRPMKEPR TGVGAAVIDN
YLYVVGGHSG SSYLNTVQKY DPISDTWLDS AGMIYCRCNF GLTAL
//
