ID H2R1P8_PANTR Unreviewed; 582 AA.
AC H2R1P8; A0A2J8M040;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Intracisternal A particle-promoted polypeptide {ECO:0000313|Ensembl:ENSPTRP00000042678.4};
GN Name=IPP {ECO:0000313|Ensembl:ENSPTRP00000042678.4};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000042678.4, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000042678.4, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000042678.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04032977; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04032978; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04032979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_001159511.1; XM_001159511.5.
DR AlphaFoldDB; H2R1P8; -.
DR SMR; H2R1P8; -.
DR STRING; 9598.ENSPTRP00000042678; -.
DR PaxDb; 9598-ENSPTRP00000042678; -.
DR Ensembl; ENSPTRT00000048362.5; ENSPTRP00000042678.4; ENSPTRG00000024149.6.
DR GeneID; 469187; -.
DR KEGG; ptr:469187; -.
DR CTD; 3652; -.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000158629; -.
DR HOGENOM; CLU_004253_14_1_1; -.
DR InParanoid; H2R1P8; -.
DR OMA; CYDPRDN; -.
DR OrthoDB; 5472491at2759; -.
DR TreeFam; TF329218; -.
DR Proteomes; UP000002277; Chromosome 1.
DR Bgee; ENSPTRG00000024149; Expressed in testis and 21 other cell types or tissues.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR CDD; cd18466; BACK_KLHL27_IPP; 1.
DR CDD; cd18256; BTB_POZ_KLHL27_IPP; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR030104; BTB_POZ_IPP.
DR InterPro; IPR047067; IPP_BACK.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 4.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 37..104
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 582 AA; 65592 MW; 25C6E2EF4E26438B CRC64;
MANEDCPKAA DSPFSSDKHA QLILAQINKM RNGQHFCDVQ LQVGQESFKA HRLVLAASSP
YFAALFTGGM KESSKDVVPI LGIEAGIFQI LLDFIYTGIV NIGVNNVQEL IIAADMLQLT
EVVHLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEFSEN YIHVHFLEVH SGEEFLALTK
DQLIKILRSE ELSIEDEYQV FLAAMQWILK DLGKRRKHVV EVLDPIRFPL LPPQRLLKYI
EGVSDFNLRV ALQTLLKEYC EVCKSPKENK FCSFLQTSKV RPRKKARKYL YAVGGYTRLQ
GGRWSDSRAL SCVERFDTFS QYWTTVSSLH QARSGLGVTV LGGMVYAIGG EKDSMIFDCT
ECYDPVTKQW TTVASMNHPR CGLGVCVCYG AIYALGGWVG AEIGNTIERF DPDENKWEVV
GNMAVSRYYF GCCEMQGLIY VIGGISNEGI ELRSFEVYDP LSKRWSPLPP MGTRRAYLGV
AALNDCIYSV GGWNETQDAL HTVEKYSFEE EKWVEVASMK VPRAGMCVVA VNGLLYVSGG
RSSSHDFLAP DTHRYEVFRL KWENMCILFN DHKTLTKGIF NL
//
