ID H2R2R4_PANTR Unreviewed; 377 AA.
AC H2R2R4; A0A2J8JQU3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=ATCAY kinesin light chain interacting caytaxin {ECO:0000313|Ensembl:ENSPTRP00000044336.3};
GN Name=ATCAY {ECO:0000313|Ensembl:ENSPTRP00000044336.3,
GN ECO:0000313|VGNC:VGNC:13170};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000044336.3, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000044336.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000044336.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04058072; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2R2R4; -.
DR STRING; 9598.ENSPTRP00000044336; -.
DR PaxDb; 9598-ENSPTRP00000044336; -.
DR Ensembl; ENSPTRT00000042460.3; ENSPTRP00000044336.3; ENSPTRG00000023462.5.
DR VGNC; VGNC:13170; ATCAY.
DR eggNOG; KOG3308; Eukaryota.
DR GeneTree; ENSGT00940000158364; -.
DR HOGENOM; CLU_039135_0_0_1; -.
DR InParanoid; H2R2R4; -.
DR TreeFam; TF324164; -.
DR Proteomes; UP000002277; Chromosome 19.
DR Bgee; ENSPTRG00000023462; Expressed in dorsolateral prefrontal cortex and 9 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:Ensembl.
DR GO; GO:0043005; C:neuron projection; IEA:Ensembl.
DR GO; GO:0019894; F:kinesin binding; IEA:Ensembl.
DR GO; GO:0006915; P:apoptotic process; IBA:GO_Central.
DR GO; GO:2000212; P:negative regulation of glutamate metabolic process; IEA:Ensembl.
DR GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR InterPro; IPR022181; Bcl2-/adenovirus-E1B.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF9; CAYTAXIN; 1.
DR Pfam; PF12496; BNIP2; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 171..328
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 331..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 377 AA; 42805 MW; 9B72C88C463E1E5B CRC64;
MGTTEATLRM ENVDVKEEWQ DEDLPRPLPE ETGVELLGSP VEDTSSPPNT LNFNGAHRKR
KTLVAPEINI SLDQSEGSLL SDDFLDTPDD LDINVDDIET PDETDSLEFL GNGNELEWED
DTPVATAKNM PGDSADLFGD GTTEDGSAAN GRLWRTVIIG EQEHRIDLHM IRPYMKVVTH
GGYYGEGLNA IIVFAACFLP DSSLADYHYI MENLFLYVIS SLELLVAEDY MIVYLNGATP
RRRMPGIGWL KKCYQMIDRR LRKNLKSLII VHPSWFIRTV LAISRPFISV KFINKIQYVH
SLEDLEQLIP MEHVQIPDCV LQYEEERLKA RRESARPQPE FVLPRSEEKP EVAPVENRPA
LVSEDQETSL QPLHRSS
//
