ID H2RHS9_PANTR Unreviewed; 545 AA.
AC H2RHS9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=PAT1 homolog 2 {ECO:0000313|Ensembl:ENSPTRP00000061085.1};
GN Name=PATL2 {ECO:0000313|Ensembl:ENSPTRP00000061085.1,
GN ECO:0000313|VGNC:VGNC:10406};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000061085.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000061085.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000061085.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PAT1 family.
CC {ECO:0000256|ARBA:ARBA00009138}.
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DR EMBL; AACZ04042842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H2RHS9; -.
DR PaxDb; 9598-ENSPTRP00000061085; -.
DR Ensembl; ENSPTRT00000075168.2; ENSPTRP00000061085.1; ENSPTRG00000041536.2.
DR VGNC; VGNC:10406; PATL2.
DR eggNOG; KOG4592; Eukaryota.
DR GeneTree; ENSGT00520000055649; -.
DR HOGENOM; CLU_009778_0_0_1; -.
DR InParanoid; H2RHS9; -.
DR OMA; WSQKPDP; -.
DR TreeFam; TF323322; -.
DR Proteomes; UP000002277; Chromosome 15.
DR Bgee; ENSPTRG00000041536; Expressed in lymph node and 10 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0000932; C:P-body; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IBA:GO_Central.
DR GO; GO:0010607; P:negative regulation of cytoplasmic mRNA processing body assembly; IEA:Ensembl.
DR GO; GO:0033962; P:P-body assembly; IBA:GO_Central.
DR InterPro; IPR039900; Pat1-like.
DR InterPro; IPR019167; PAT1_dom.
DR PANTHER; PTHR21551:SF3; PROTEIN PAT1 HOMOLOG 2; 1.
DR PANTHER; PTHR21551; TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1; 1.
DR Pfam; PF09770; PAT1; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 264..402
FT /note="mRNA decay factor PAT1"
FT /evidence="ECO:0000259|Pfam:PF09770"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..62
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 61718 MW; 67ACF4ABEC7714B8 CRC64;
MKCLEGPGKT CGPLASEEEP VSACQLEKEE ENEGEEEEEQ EEEDEEDLDP DLDPDLEEEE
NDLGDPAVLG AVHNTQRALL SSPGVKAPGV LGMSLASLHF LWQTLDYLSP IPFWPTFPST
SSPAQHFGPR LPSPDPTLFC SLLTSWPPRF SHLTQLHPRH QRILQQQQHS QTPSPPAKKP
WSQQPDPYAN LMTRKEKDWV IKVQMVQLQS AKPRLDDYYY QEYYQKLEKK QADEELLGRR
NRVESLKLVT PYIPKAEAYE SVVRIEGSLG QVAVSTCFSP RRAIDAVPHG TQEQDIEAAS
SQRLRVLYRI EKMFLQLLEI EEGWKYRPPQ PCFSEQQSNQ VEKLFQTLKT QEQNNLEEAA
DGFLQVLSVR KGKALVARLL PFLPQDQAVT ILLAITHHLP LLVRRDVADQ ALQMLFKPLG
KCISHLTLHE LLQGLQGLTL LPPGSSERPV TVVLQNQFGI SLLYALLSHG EQLVSLHSSL
EEPNSDHTAW TDMVVLIAWE IAQMPTASLA EPLAFPSNLL PLFCHHVDKQ LVQQLEARME
FAWIY
//
