ID   H2SDX0_TAKRU            Unreviewed;       476 AA.
AC   H2SDX0;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   17-JUN-2020, sequence version 3.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Family with sequence similarity 172 member A {ECO:0000313|Ensembl:ENSTRUP00000010601.3};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000010601.3, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000010601.3, ECO:0000313|Proteomes:UP000005226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21551351;
RA   Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA   Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT   "Integration of the genetic map and genome assembly of fugu facilitates
RT   insights into distinct features of genome evolution in teleosts and
RT   mammals.";
RL   Genome Biol. Evol. 3:424-442(2011).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000010601.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; H2SDX0; -.
DR   STRING; 31033.ENSTRUP00000010601; -.
DR   Ensembl; ENSTRUT00000010659.3; ENSTRUP00000010601.3; ENSTRUG00000004456.3.
DR   GeneTree; ENSGT00530000063907; -.
DR   HOGENOM; CLU_048484_3_0_1; -.
DR   InParanoid; H2SDX0; -.
DR   OMA; PGMWARS; -.
DR   Proteomes; UP000005226; Chromosome 21.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR048263; Arb2.
DR   PANTHER; PTHR21357:SF5; COTRANSCRIPTIONAL REGULATOR FAM172A HOMOLOG; 1.
DR   PANTHER; PTHR21357; UNCHARACTERIZED; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          258..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          454..476
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        276..310
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        461..476
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   476 AA;  53828 MW;  EDE57E278A730C13 CRC64;
     MTLEEAEPPD QGRRTTSFSS SKIPLELVTL TRSSGGGHVR TDLARAGAEN ISVTAPIQLP
     HPSAASCTPC VTMAQGSGQE DREKTTALKD LLSRIDLDEL MKKDEPPFSF PKTLEEFEYA
     FNEDGQLRHT ETGEPFVFNA REDLHRWNQK RYEALGEIIT LYVYELLEKT CNMTKAILPV
     DASPDEPTSF IYLTPDALLN PSKLLVLIQG SGVERAGQWA RRLIINQDLD SGTQIPFITR
     AIQDGYGVVV LNPNENYQEV EKPSRSPPPT PPGDPPDEPA EKRERKDDKE SKKKREFYEK
     YRNPQKEMET DRIPVRENAS SEEHVVHVWD HFVSKAEAKN VFIMAHSYGG LSFVELMNQR
     ETDVKNRVRA VAFADSAHNI WHQDTSKGTQ DWMQQHCCNW VSSSEPLDAP LDSMLPDCPR
     VSAGTERHEL TPWMSFNSIF RFFNEVLELK EDDKAEGPFS AVTTRSGSLK PNHQNL
//