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Database: UniProt
Entry: H2T434_TAKRU
LinkDB: H2T434_TAKRU
Original site: H2T434_TAKRU 
ID   H2T434_TAKRU            Unreviewed;      1773 AA.
AC   H2T434;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   20-DEC-2017, entry version 37.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSTRUP00000019422};
GN   Name=LOC101061989 {ECO:0000313|Ensembl:ENSTRUP00000019422};
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae;
OC   Takifugu.
OX   NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000019422, ECO:0000313|Proteomes:UP000005226};
RN   [1] {ECO:0000313|Ensembl:ENSTRUP00000019422}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSTRUP00000019422};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B.,
RA   Yamada T., Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D.,
RA   Shimada A., Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A.,
RA   Asakawa S., Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K.,
RA   Sugano S., Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F.,
RA   Nomoto H., Nogata K., Morishita T., Endo T., Shin-I T., Takeda H.,
RA   Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome
RT   evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSTRUP00000019422}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSTRUP00000019422}.
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DR   Ensembl; ENSTRUT00000019500; ENSTRUP00000019422; ENSTRUG00000007814.
DR   GeneTree; ENSGT00830000128242; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028809; Na_channel_a10su.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   InterPro; IPR024583; Na_trans_cytopl.
DR   PANTHER; PTHR10037:SF208; PTHR10037:SF208; 1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   Pfam; PF06512; Na_trans_assoc; 1.
DR   Pfam; PF11933; Na_trans_cytopl; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005226};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    121    147       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    159    178       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    198    218       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    230    247       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    253    273       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    393    420       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    727    745       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    757    780       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    837    865       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    895    913       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    925    950       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1223   1241       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1262   1280       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1339   1365       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1462   1485       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1544   1562       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1574   1592       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1599   1624       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1661   1689       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      131    426       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      524    620       Na_trans_cytopl. {ECO:0000259|Pfam:
FT                                PF11933}.
FT   DOMAIN      727    955       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      964   1217       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN     1221   1494       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1543   1773       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED       21     41       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1773 AA;  200709 MW;  05C55C867D8AC8C5 CRC64;
     MAGCVFPMGP ESFQRFTPDS LAAIEQRIIQ EEARLKKQYK EDLGDVELPQ ARPDLEAGKQ
     LPRIFADIPS HLVGVPLEDI DPYYFRDKRT FIVLNKGKAI FRFSATSALY FFSPFHPVRR
     IAIKILVHSY TLFSLFIMCT ILTNCCFMAM SEPANWAKYL EYTFTGIYTF ESLIKILARG
     FCVGPFTFLR DPWNWLDFSV IVMAYVTEFV DLGNVSALRT FRVLRALKTI SVIPGLKTIV
     GALIQSVKKL ADVMILTVFC LSVFALIGLQ LFMGNLRQKC VRSTAHCVND SLPANASFFC
     NNKTWTSMKD FINEEENFYK AEGAKDALIC GNGSDAGKCP DGFECLKTGR NPNYGYTSFD
     TFGWAFLSLF RLMTQDCWEN LYHQTLRSAG KTYMVFFVVV IFLGSFYLIN LILAVVAMAY
     EEQNQATIVE ECQKEREFQV AMERLKKDQQ AAAQKALDSD SVMSPELSPF ALPLDHQEGR
     RQSQVLVGVA EAEANLSEEK LLQVDVTDGG KPVHPLLARS FSAKTRRSSQ VSSIFNFRLR
     SRGSEGEMAD DEYSVPEDVI EGVGGGTYSG GTFSGILSHP WPKRRPSTYS TTSRSSQVFY
     PTLNINGKLF VTMDQNGVSP PPLQGQLPAC TMEKVNVRHQ ILQAPTSTTE LSTMLLPRPS
     SLQGSVSRGR ALSAASYLTD AMEELEEAHK RCHPCWYAFA HRFLVWECCP CWLKVKQLVK
     VMVMDPFLDL AITICIVLNT LFMAMEHYPM TEEFNGMLSI GNLVFSGIFT AEMVLKIIAL
     DPYYYFQTGW NIFDSIIVCL SLMELGLSNV EGLSVLRSFR LLRVFKLARS WPTLNTLIKI
     IGNSMGALGN LTLVLAIIVF IFAVVGMQLF GKNYQDCVCK ISKDCTLPRW HMKDFFHSFL
     IVFRVLCGEW IESMWDCMEV AGQPLCILVF MLVMVIGNLV LLNLFLALLL SSFSSDNLSA
     PDEDGEMNNL QIAIHRITRG LAWCRKQVVD FFNGNLKRRR QKQKEAKAMM KLKRLSSIHM
     EVNGAVIGAE TSEPPNVDEP QFNKSIQGLC GCSRAPNVPI APGESDVEFP EDEDEDGEEE
     EEESEASQEE EERIKGEMRS QFRPSRLSFQ VSGQTDLTQL GVHNNSTDAE YLITETKTRK
     SSLAANQKDE VSLSEGSTVD LRKPGEEEDE YSEMAEEAMD PENCFPDVCV ARFQCCDLNT
     TAGLGQMWWR TRKTCYQIVE HSWFESFIIF MILLSSGALA FEDIYIEQRK VVKVILEYAD
     KIFTYIFILE MLLKWLAYGF KKYFTNYWCW LDFLIVDVSL ISLVANTLGY SDFAAIKSLR
     TLRALRPLRA LSRFEGMRVV VNALIGAIPS IMNVLLVCLI FWLIFSIMGV NLFAGKFGRC
     VNRTGHIYEA AFINNKSECE ALNDTSLFYW TKVKVNFDNV GAGYLALLQV ATFKGWTDIM
     FAAVDSRAVE EQPIKEVNLY MYLYFVIFII FGSFFTLNLF IGVIIDNFNQ QKRKLGGQDI
     FMTEEQKKYY NAMKKLGSKK PQKPIPRPLN SLQGFFFDLT GKQAFDIIIM VLIILNMITM
     MVETDEQSPQ MEYILNNINL AFIVIFTTEC LIKIVALRYY FFTVGWNIFD FVVVILSIVG
     IVLADIIEKY FVSPTLFRVI RLARIGRILR LIRGAKGIRT LLFALMMSLP ALFNIGLLLF
     LVMFIYAIFG MANFAYVKRQ AGIDDMFNFE TFGNSMICLF QITTSAGWDT LLSPILNNSP
     EECNPNIPHT GTTVRGNCGN PSVGITFFVT YII
//
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