ID H2T5K1_TAKRU Unreviewed; 1474 AA.
AC H2T5K1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=DNA-binding protein RFX7-like {ECO:0000313|Ensembl:ENSTRUP00000019940.3};
GN Name=RFX7 {ECO:0000313|Ensembl:ENSTRUP00000019940.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000019940.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000019940.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000019940.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 31033.ENSTRUP00000019940; -.
DR Ensembl; ENSTRUT00000020021.3; ENSTRUP00000019940.3; ENSTRUG00000008008.3.
DR eggNOG; KOG3712; Eukaryota.
DR GeneTree; ENSGT01050000244970; -.
DR HOGENOM; CLU_252972_0_0_1; -.
DR InParanoid; H2T5K1; -.
DR OMA; MVKFRAA; -.
DR TreeFam; TF321340; -.
DR Proteomes; UP000005226; Chromosome 9.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 6.10.140.1290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR039779; RFX-like.
DR InterPro; IPR040889; RFX5_N.
DR InterPro; IPR047009; RFX5_N_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12619:SF2; DNA-BINDING PROTEIN RFX7; 1.
DR PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR Pfam; PF18326; RFX5_N; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 98..173
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 281..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 906..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1067..1173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1307..1342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..945
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1071..1125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1132..1173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1307..1331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1474 AA; 157680 MW; 0A37B3CCA9653A3B CRC64;
MADDQQQPGQ KPASGLGSLP ALVPGLQGPE ANALQFKIKN SICKSVQSKV DSILQDVEKF
TDIEKLYLYL KLPSGPSSGN DKSDQSSMSS SRTQQMYAFN WIRNHLEEHQ ETSLPKQEVY
DEYKSYCDNL GYNPLSAADF GKIMKNVFPT MKARRLGMRG KSKYCYSGLR KKAFVHMPSL
PNLDLQKSGD GCELMEPTGQ SPSAEDDMRS AACGLVCEWA QKVLSRQFDN VEDLARFLLN
SHYIGTKSMA ALTVMTGTPT GMKTPTPASA FVPTAEANTF QPQVKTLPSP SVDAKQQLQR
KIQKKQQEQK LHSPLPSETP IKRTEASTPG PTIPCGSPAL LSPQPTIGIV VAAVPSPVTV
QRNRQLMTSP SPVGTAEGKV LPVNFQVVAQ SLKQSPKTPQ NISASPVSDR LARHGTRYAQ
ILPKPSATSA ITLRSPPTLL ITNSPIKTVM PTSHVSSVNV VKMTAIALAP SSSNATARPA
SAGVTTIAAS DDSQTTQSVS ALTPHSPVVR PGAPVSSTTL SADAKVKSEG GNDGSASLGT
EKTAVGAKEE RTSKFRAASE PNFLVKCSLA PARLKNDAAC SPSSVAAAGT QDSNNSNCHD
STLYLTVDNQ NGTTSSSDSS AVTLVTKDPS LDARSARKRT SSTGESHVIP VKRVFISQQP
LAVVDNPKPG VSAAVKRIPR PGTPARPESA PCKVTVKHTS TGPPQILALS DAPVTHSQPV
VKPQALVVKP QVLSLSTDTS TGPAGNDASD QVLLQQISGD PRAIPANSGA HKASVMSDLK
STIWEEGQLD ELRKQAFAQQ IPAEHKQAPS DPLAIAAQPS EASGQLTLTQ EMVDFAGSQP
NMDYFPFNDD DMTQDSIVEE LVQMEEQMKL KGLFSSCVDV SLPGQPSSNQ GSLLNAHQAG
ATFYHSAHSS TTPVQTPTPT PTPTPTPTPT SEMTLSHSLT RESPCSRMAP ITPVDSAMGR
HTPISTPLSN CSSSVPPSPV ECRNPFAFTP INSSITGYHD ASIVSSSPVK PMQRPMATHP
DKAKLEWINN RYNSSSASPL SNHSIGILPS YQDLVDDQFR KPHAFAIPGQ SFQPQPRQDS
SHFGRLTPIS PVQQQQQQQQ QQTPQQQQQQ HQLVTTVTTP TKQESFAVPA PLDSKASTSS
ASGTFRCRSV SPAVRQRNFS GNSGPPTTTT NTATTTRAVH SPFNTTEVLS IFSNTQTVSS
VHSMVQRSQS VPLSIMMQSE MLPVQAQNNT AKITTVLLSK LEADADDSVR GLGINNLPSN
YTARMDLTQM LESTCGFPGG TSHQSQLPVD SSPAAFELQQ HGYLTTGSGE QVNFSTGESQ
AQAGPGEQDP PQNQENPVPA PPQLLLQSTQ QQDGEDEQQQ LDFNNTVKDL LGDDGLNPSS
QLVGQVASEL NAVASDFSSD VRLTSDLSSS ITDLNTLDST LLFDPNQQQE QYEDSTLEEL
KNDPLFQQIC SDTVNSGFDW LESKDQPTTV EMLG
//
