ID H2T9Y7_TAKRU Unreviewed; 510 AA.
AC H2T9Y7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Protein disulfide-isomerase-like {ECO:0000313|Ensembl:ENSTRUP00000021477.3};
GN Name=LOC101064129 {ECO:0000313|Ensembl:ENSTRUP00000021477.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000021477.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000021477.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000021477.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein disulfide isomerase family.
CC {ECO:0000256|ARBA:ARBA00006347}.
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DR AlphaFoldDB; H2T9Y7; -.
DR STRING; 31033.ENSTRUP00000021477; -.
DR Ensembl; ENSTRUT00000021565.3; ENSTRUP00000021477.3; ENSTRUG00000008569.3.
DR eggNOG; KOG0190; Eukaryota.
DR GeneTree; ENSGT00940000166046; -.
DR HOGENOM; CLU_025879_1_0_1; -.
DR InParanoid; H2T9Y7; -.
DR OMA; YKMTPQT; -.
DR OrthoDB; 5399045at2759; -.
DR TreeFam; TF106381; -.
DR Proteomes; UP000005226; Chromosome 17.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR CDD; cd02995; PDI_a_PDI_a'_C; 1.
DR CDD; cd02982; PDI_b'_family; 1.
DR CDD; cd02981; PDI_b_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 4.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR18929; PROTEIN DISULFIDE ISOMERASE; 1.
DR PANTHER; PTHR18929:SF58; PROTEIN DISULFIDE-ISOMERASE-LIKE PROTEIN OF THE TESTIS; 1.
DR Pfam; PF00085; Thioredoxin; 2.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 4.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..510
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025530362"
FT DOMAIN 346..475
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT COILED 460..487
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 510 AA; 57480 MW; 4384A04844CC5A7D CRC64;
MNRSLLLGVL ILGLPFVNGD ADKWSTGNDG VLQLNSGNFD RALREHEQLL VHFYVPLSGQ
GHQVSAAFEG AAVELQGSEV KLAVVDAAKE KDLAKELNVA GSSEIRLYVS GDKHSPVVCP
VPQSSTSILT WLRRRAGSPG DLVRDLSQLE TSEDVTVVGF FRELNQEYVQ TFYATAIQLP
DVSFAITQDN EVTHKYGLTY DVVFLLRKSK LIQAYKLMPQ TSKEELMVFI SVYQMDPVTE
YTGKTANQIL SSPVLNHALL FIRKSSADFN HVYSAFNNAA QSFRVKILFV WVNVDEPRNG
RLMEYFRVRD FEAPLIRVVN LTSHVTYQLP SDTLEVESIK TFCASYLEGK AKPKMQSEAI
PEGWDTQPVK ELVGMNLEEV AFNPNKTVFV MFYLPYSPAS RALFPLWEEL AEATEGREGV
VIARIDASAN DINLSPQGAY PTLCLFPALH AERMVVYSGE RRLEDLIQFL NTEMEKAKRD
RVQEDEDRRK YIKDIKDEEA KKADKSKDEL
//
