ID H2TI11_TAKRU Unreviewed; 181 AA.
AC H2TI11;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 3.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Malignant T-cell-amplified sequence {ECO:0000256|PIRNR:PIRNR005067};
GN Name=mcts1 {ECO:0000313|Ensembl:ENSTRUP00000024311.3};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000024311.3, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000024311.3, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000024311.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR005067}.
CC -!- SIMILARITY: Belongs to the MCTS1 family.
CC {ECO:0000256|ARBA:ARBA00008955, ECO:0000256|PIRNR:PIRNR005067}.
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DR RefSeq; XP_003970599.1; XM_003970550.2.
DR AlphaFoldDB; H2TI11; -.
DR Ensembl; ENSTRUT00000024410.3; ENSTRUP00000024311.3; ENSTRUG00000009679.3.
DR GeneID; 101078325; -.
DR KEGG; tru:101078325; -.
DR CTD; 28985; -.
DR eggNOG; KOG2523; Eukaryota.
DR GeneTree; ENSGT00550000074964; -.
DR HOGENOM; CLU_090468_0_1_1; -.
DR InParanoid; H2TI11; -.
DR OMA; SINKGHG; -.
DR OrthoDB; 5036262at2759; -.
DR TreeFam; TF315123; -.
DR Proteomes; UP000005226; Chromosome 14.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd11609; MCT1_N; 1.
DR CDD; cd21155; PUA_MCTS-1-like; 1.
DR Gene3D; 3.10.400.20; -; 1.
DR InterPro; IPR016437; MCT-1/Tma20.
DR InterPro; IPR041366; Pre-PUA.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR004521; Uncharacterised_CHP00451.
DR NCBIfam; TIGR00451; unchar_dom_2; 1.
DR PANTHER; PTHR22798:SF0; MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1; 1.
DR PANTHER; PTHR22798; MCT-1 PROTEIN; 1.
DR Pfam; PF17832; Pre-PUA; 1.
DR Pfam; PF01472; PUA; 1.
DR PIRSF; PIRSF005067; Tma_RNA-bind_prd; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR005067};
KW Growth regulation {ECO:0000256|ARBA:ARBA00022604};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 93..171
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 181 AA; 20542 MW; FB1DC6E2AF7A57C7 CRC64;
MFKKFDEKEN VSNCIQLKTS VIKGIKNQLL DQFPDIEAWL NHIMPKKDPV KIVRCHEHIE
ILTVNGELLF FRQREGPFYP TLRLLHKYPF ILPHQQVDKG AIKFVLSGAN IMCPGLTSPG
AKLYPADADT VVAIMAEGKQ HALCVGVMKM SAESIEKVNK GIGIENVHYL NDGLWHMKTY
K
//
